SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mti'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
ASN A  93
 None
 0.97A 3eeyA-3mtiA:
27.0		 3eeyA-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASN A  32
ASP A  33
GLY A  75
HIS A  76
ASN A  93
 None
 0.53A 3eeyA-3mtiA:
27.0		 3eeyA-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
ASN A  93
 None
 0.97A 3eeyB-3mtiA:
27.0		 3eeyB-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		8 / 12 THR A  27
GLY A  29
ASN A  32
ASP A  33
GLN A  50
GLY A  75
HIS A  76
ASN A  93
 None
 0.54A 3eeyB-3mtiA:
27.0		 3eeyB-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
THR A 110
 None
 0.89A 3eeyC-3mtiA:
27.1		 3eeyC-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASP A  33
GLY A  75
HIS A  76
ASN A  93
THR A 110
 None
 0.53A 3eeyC-3mtiA:
27.1		 3eeyC-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		3 / 3 ASN A  32
ASP A  48
GLN A  50
 None
 0.31A 3eeyC-3mtiA:
27.1		 3eeyC-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		5 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
 None
 0.92A 3eeyD-3mtiA:
27.0		 3eeyD-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
GLY A  29
ASP A  33
GLY A  75
HIS A  76
ASN A  93
 None
 0.56A 3eeyD-3mtiA:
27.0		 3eeyD-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		3 / 3 ASN A  32
ASP A  48
GLN A  50
 None
 0.33A 3eeyD-3mtiA:
27.0		 3eeyD-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
THR A 110
 None
 0.88A 3eeyE-3mtiA:
27.1		 3eeyE-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASP A  33
GLY A  75
HIS A  76
ASN A  93
THR A 110
 None
 0.50A 3eeyE-3mtiA:
27.1		 3eeyE-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		3 / 3 ASN A  32
ASP A  48
GLN A  50
 None
 0.31A 3eeyE-3mtiA:
27.1		 3eeyE-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
ASN A  30
GLY A  75
HIS A  76
ASN A  93
THR A 110
 None
 1.30A 3eeyF-3mtiA:
27.1		 3eeyF-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		8 / 12 THR A  27
GLY A  29
ASN A  32
ASP A  33
GLY A  75
HIS A  76
ASN A  93
THR A 110
 None
 0.54A 3eeyF-3mtiA:
27.1		 3eeyF-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		5 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
 None
 0.91A 3eeyH-3mtiA:
27.2		 3eeyH-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASN A  32
ASP A  33
GLY A  75
HIS A  76
ASN A  93
 None
 0.56A 3eeyH-3mtiA:
27.2		 3eeyH-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		5 / 12 THR A  27
GLY A  29
ASN A  30
GLY A  75
HIS A  76
 None
 0.91A 3eeyI-3mtiA:
27.2		 3eeyI-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASN A  32
ASP A  33
GLY A  75
HIS A  76
ASN A  93
 None
 0.56A 3eeyI-3mtiA:
27.2		 3eeyI-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASN A  30
ASP A  48
GLY A  75
HIS A  76
ASN A  93
 None
 0.88A 3eeyJ-3mtiA:
27.2		 3eeyJ-3mtiA:
44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASP A  33
ASP A  48
GLY A  75
HIS A  76
ASN A  93
 None
 0.46A 3eeyJ-3mtiA:
27.2		 3eeyJ-3mtiA:
44.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		3 / 3 HIS A 109
GLU A 113
ASN A  78
 None
 0.99A 4bupB-3mtiA:
undetectable		 4bupB-3mtiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA404_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		4 / 5 SER A  41
LYS A  42
LEU A  17
ASP A  18
 None
 1.20A 4ifxA-3mtiA:
undetectable		 4ifxA-3mtiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		4 / 5 SER A  41
LYS A  42
LEU A  17
ASP A  18
 None
 1.17A 4ig1A-3mtiA:
undetectable		 4ig1A-3mtiA:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		5 / 12 THR A  27
GLY A  29
ASN A  30
HIS A  76
ASN A  93
 None
 1.13A 4pooA-3mtiA:
24.9		 4pooA-3mtiA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		5 / 12 THR A  27
GLY A  29
ASP A  33
HIS A  76
ASN A  93
 None
 0.78A 4pooA-3mtiA:
24.9		 4pooA-3mtiA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		6 / 12 THR A  27
GLY A  29
ASN A  30
ASP A  48
GLN A  50
HIS A  76
 None
 0.98A 4pooB-3mtiA:
25.1		 4pooB-3mtiA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		7 / 12 THR A  27
GLY A  29
ASP A  33
ASP A  48
GLN A  50
HIS A  76
ASN A  93
 None
 0.86A 4pooB-3mtiA:
25.1		 4pooB-3mtiA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		4 / 5 SER A  41
LYS A  42
LEU A  17
ASP A  18
 None
 1.20A 4xdtA-3mtiA:
undetectable		 4xdtA-3mtiA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		4 / 4 ASP A  25
GLY A  29
ASP A  48
ASP A  74
 None
 1.02A 5e72A-3mtiA:
15.6		 5e72A-3mtiA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		3 / 3 HIS A 109
GLU A 113
ASN A  78
 None
 0.96A 5wbvA-3mtiA:
undetectable		 5wbvA-3mtiA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		3 / 3 HIS A 109
GLU A 113
ASN A  78
 None
 0.95A 5wbvB-3mtiA:
undetectable		 5wbvB-3mtiA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 3mti RRNA METHYLASE
(Streptococcus
thermophilus) 		4 / 8 LEU A 153
VAL A 176
LEU A 178
ILE A 130
 None
 0.76A 6cb4A-3mtiA:
undetectable		 6cb4A-3mtiA:
17.35