SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mtk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_A_IMNA1_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3mtk	DIGUANYLATE CYCLASE/PHOSPHODIEST ERASE (Caldicellulosiru ptor saccharolyticus)	5 / 10	ARG A 287 ILE A 257 GLY A 259 LEU A 199 ILE A 274	None	1.48A	3adsA-3mtkA: undetectable	3adsA-3mtkA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3Q_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3mtk	DIGUANYLATE CYCLASE/PHOSPHODIEST ERASE (Caldicellulosiru ptor saccharolyticus)	5 / 12	MET A 288 PHE A 272 LEU A 199 PRO A 200 TYR A 296	None	1.06A	4p3qA-3mtkA: undetectable	4p3qA-3mtkA: 23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R3A_A_RBFA402_1 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	3mtk	DIGUANYLATE CYCLASE/PHOSPHODIEST ERASE (Caldicellulosiru ptor saccharolyticus)	5 / 12	ALA A 264 ILE A 274 ILE A 250 LEU A 292 MET A 288	None	1.20A	4r3aA-3mtkA: 2.1	4r3aA-3mtkA: 19.10