SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mtq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		4 / 4 LEU A  44
GLY A  70
ASP A  66
TYR A  37
 None
 1.27A 1oxrA-3mtqA:
undetectable		 1oxrA-3mtqA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		4 / 7 ARG A  54
HIS A   4
PHE A  55
ILE A  31
 None
 1.24A 1tdnA-3mtqA:
undetectable		 1tdnA-3mtqA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A  62
LEU A  95
LEU A  91
GLY A  90
ILE A   6
 None
 1.04A 4c9lA-3mtqA:
undetectable		 4c9lA-3mtqA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A  62
LEU A  95
LEU A  91
GLY A  90
ILE A   6
 None
 1.00A 4c9lB-3mtqA:
undetectable		 4c9lB-3mtqA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		5 / 10 ILE A  64
LEU A  44
VAL A  52
LEU A  51
PHE A   7
 None
 1.48A 4r3aB-3mtqA:
undetectable		 4r3aB-3mtqA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A  90
HIS A  10
ASP A  66
ASN A  73
 None
 1.07A 5nnwD-3mtqA:
undetectable		 5nnwD-3mtqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A  90
HIS A  10
ASP A  66
ASN A  73
 None
 1.05A 5no9D-3mtqA:
undetectable		 5no9D-3mtqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3mtq PUTATIVE
PHOSPHOENOLPYRUVATE-
DEPENDENT SUGAR
PHOSPHOTRANSFERASE
SYSTEM (PTS)
PERMEASE
(Klebsiella
pneumoniae) 		3 / 3 HIS A   4
HIS A  32
ARG A  54
 None
 0.99A 6b58A-3mtqA:
undetectable		 6b58A-3mtqA:
13.50