SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mtr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3mtr NEURAL CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 8 SER A 591
PHE A 593
ALA A 515
LEU A 566
 None
 0.89A 2bxkA-3mtrA:
undetectable		 2bxkA-3mtrA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 3mtr NEURAL CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 8 SER A 591
PHE A 593
ALA A 515
LEU A 566
 None
 0.88A 2bxmA-3mtrA:
undetectable		 2bxmA-3mtrA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3mtr NEURAL CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 5 ALA A 405
LEU A 408
LYS A 407
ASN A 483
 None
 1.14A 4g19A-3mtrA:
undetectable		 4g19A-3mtrA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3mtr NEURAL CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 7 LEU A 444
THR A 435
THR A 480
VAL A 482
 None
 0.83A 4ik7A-3mtrA:
undetectable		 4ik7A-3mtrA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3mtr NEURAL CELL ADHESION
MOLECULE 1
(Homo
sapiens) 		4 / 6 ASP A 469
PRO A 446
TYR A 477
LEU A 464
 None
 1.32A 5bmvB-3mtrA:
undetectable		 5bmvB-3mtrA:
21.38