SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mtt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA
(Homo
sapiens) 		4 / 6 LYS A 558
PRO A 565
TYR A 460
LEU A 563
 None
 1.34A 5bmvB-3mttA:
undetectable		 5bmvB-3mttA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA
(Homo
sapiens) 		4 / 7 LEU A 581
TRP A 580
GLY A 443
ALA A 444
 None
 0.84A 5f1aB-3mttA:
undetectable		 5f1aB-3mttA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3mtt PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT BETA
(Homo
sapiens) 		4 / 8 THR A 540
LEU A 542
ILE A 481
LEU A 546
 None
 0.92A 5g48A-3mttA:
undetectable		 5g48A-3mttA:
17.72