SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mue'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 11 HIS A  34
HIS A  37
GLY A 149
ASP A 152
ILE A 178
 EOH  A 292 (-4.3A)
None
None
None
EOH  A 292 ( 4.0A)
 1.11A 1jzsA-3mueA:
undetectable		 1jzsA-3mueA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 11 HIS A  34
GLY A  36
HIS A  37
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
 0.96A 1pg2A-3mueA:
3.6		 1pg2A-3mueA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 12 HIS A  34
GLY A  36
HIS A  37
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
 1.06A 1qu2A-3mueA:
4.1		 1qu2A-3mueA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 4 LEU A 282
ILE A 245
ILE A 211
ALA A 212
 None
EOH  A 296 (-4.9A)
None
None
 0.79A 2i30A-3mueA:
undetectable		 2i30A-3mueA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 8 LEU A 215
LEU A 222
ASP A 247
ARG A 220
 None
 0.91A 2j2pA-3mueA:
undetectable
2j2pB-3mueA:
undetectable		 2j2pA-3mueA:
19.93
2j2pB-3mueA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 6 LEU A  10
LEU A   9
ILE A  14
ARG A  15
 None
 1.02A 2rlfA-3mueA:
undetectable
2rlfB-3mueA:
undetectable		 2rlfA-3mueA:
11.06
2rlfB-3mueA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASN A 139
SER A 135
TYR A 168
VAL A 109
 None
 1.13A 2uz2A-3mueA:
undetectable		 2uz2A-3mueA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 11 HIS A  34
GLY A  36
HIS A  37
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
 0.95A 2x1lA-3mueA:
5.0		 2x1lA-3mueA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 12 HIS A  34
GLY A  36
HIS A  37
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
 0.90A 2x1lB-3mueA:
4.3		 2x1lB-3mueA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 11 HIS A  34
GLY A  36
HIS A  37
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
 0.93A 2x1lC-3mueA:
5.5		 2x1lC-3mueA:
19.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		6 / 8 GLN A  61
ARG A 123
HIS A 126
VAL A 130
ASP A 152
GLN A 155
 GOL  A 291 ( 2.9A)
EOH  A 298 (-3.8A)
EOH  A 298 (-4.6A)
GOL  A 291 ( 4.3A)
None
GOL  A 291 (-3.4A)
 0.67A 3uy4A-3mueA:
31.1		 3uy4A-3mueA:
42.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 8 ARG A  73
ASP A  78
LEU A  75
ILE A   3
 None
 0.88A 4k0bA-3mueA:
undetectable		 4k0bA-3mueA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 8 ARG A  73
ASP A  78
LEU A  75
ILE A   3
 None
 0.99A 4l7iA-3mueA:
undetectable		 4l7iA-3mueA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		3 / 3 ASP A 276
ASN A 206
SER A 279
 None
 0.75A 4obwA-3mueA:
undetectable		 4obwA-3mueA:
23.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		7 / 12 HIS A  34
GLY A  36
LEU A  40
GLN A  61
TYR A  71
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
GOL  A 291 ( 2.9A)
None
None
None
 0.51A 5hg0A-3mueA:
26.4		 5hg0A-3mueA:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		6 / 12 HIS A  34
GLY A  36
LEU A  40
GLY A 149
LYS A 151
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
None
 0.57A 5hg0A-3mueA:
26.4		 5hg0A-3mueA:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		7 / 12 HIS A  34
GLY A  36
HIS A  37
LEU A  40
GLY A 149
LYS A 151
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
None
None
 0.67A 5hg0B-3mueA:
26.4		 5hg0B-3mueA:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		7 / 12 HIS A  34
GLY A  36
HIS A  37
LEU A  40
TYR A  71
GLY A 149
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
None
None
 0.46A 5hg0B-3mueA:
26.4		 5hg0B-3mueA:
38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		6 / 12 HIS A  34
GLY A  36
HIS A  37
VAL A 134
LYS A 151
ASP A 152
 EOH  A 292 (-4.3A)
EOH  A 292 ( 4.1A)
None
None
None
None
 1.40A 5hg0B-3mueA:
26.4		 5hg0B-3mueA:
38.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		5 / 12 SER A  54
GLN A 155
VAL A 175
LEU A  40
HIS A  37
 None
GOL  A 291 (-3.4A)
None
None
None
 1.20A 5kocB-3mueA:
undetectable		 5kocB-3mueA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 3mue PANTOTHENATE
SYNTHETASE
(Salmonella
enterica) 		4 / 6 LEU A  40
CYH A 147
GLY A 174
ARG A  47
 None
 1.27A 6gtqB-3mueA:
undetectable
6gtqD-3mueA:
undetectable		 6gtqB-3mueA:
20.70
6gtqD-3mueA:
12.01