SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3muo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		3 / 3 ALA A  50
VAL A  45
TRP A  44
 None
 0.88A 1kqeA-3muoA:
undetectable
1kqeE-3muoA:
undetectable		 1kqeA-3muoA:
2.11
1kqeE-3muoA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		3 / 3 ALA A  50
VAL A  45
TRP A  44
 None
 0.85A 1kqeB-3muoA:
undetectable
1kqeD-3muoA:
undetectable		 1kqeB-3muoA:
2.11
1kqeD-3muoA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		3 / 3 TRP A  44
ALA A  50
VAL A  45
 None
 0.88A 1kqeB-3muoA:
undetectable
1kqeD-3muoA:
undetectable		 1kqeB-3muoA:
2.11
1kqeD-3muoA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		3 / 3 TRP A  44
ALA A  50
VAL A  45
 None
 0.86A 1kqeA-3muoA:
undetectable
1kqeE-3muoA:
undetectable		 1kqeA-3muoA:
2.11
1kqeE-3muoA:
2.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 10 ASP A 582
ASN A 539
GLY A 457
GLY A 492
GLU A 493
 None
 1.03A 1mehA-3muoA:
undetectable		 1mehA-3muoA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 6 VAL A 238
THR A 239
LEU A 263
ARG A 243
 None
 0.92A 1s8fB-3muoA:
undetectable		 1s8fB-3muoA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 10 GLY A 502
ALA A 501
GLY A 492
PRO A 436
VAL A 435
 None
 0.97A 2aquA-3muoA:
undetectable		 2aquA-3muoA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLY A 576
PHE A 573
ALA A 575
TYR A 233
ARG A 201
 None
 1.25A 2avdA-3muoA:
undetectable		 2avdA-3muoA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 LEU A 364
HIS A 331
GLU A 340
ALA A 347
 None
SO4  A 807 (-4.1A)
None
None
 1.03A 2bnnA-3muoA:
undetectable
2bnnB-3muoA:
undetectable		 2bnnA-3muoA:
15.62
2bnnB-3muoA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLY A 563
GLY A 540
GLY A 537
ALA A 561
ASP A 512
 None
None
ZPR  A 702 (-3.3A)
ZPR  A 702 ( 4.6A)
None
 1.08A 2dpmA-3muoA:
undetectable		 2dpmA-3muoA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		6 / 12 GLY A 502
ALA A 501
GLY A 495
GLY A 492
PRO A 436
VAL A 435
 None
 0.99A 2fxeA-3muoA:
undetectable		 2fxeA-3muoA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLY A 502
ALA A 501
GLY A 492
PRO A 436
VAL A 435
 None
 0.94A 2ieoA-3muoA:
undetectable		 2ieoA-3muoA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 HIS A 155
PRO A 168
SER A 145
SER A 149
 None
 1.24A 2p02A-3muoA:
undetectable		 2p02A-3muoA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 7 ILE A 454
ILE A 438
LEU A 437
ILE A 439
 ZPR  A 702 ( 4.3A)
None
None
None
 0.90A 2q83A-3muoA:
undetectable		 2q83A-3muoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLN A  58
TYR A 679
HIS A 645
GLN A 647
 None
SUC  A 703 (-3.9A)
None
None
 1.19A 2vxaA-3muoA:
undetectable
2vxaB-3muoA:
undetectable
2vxaK-3muoA:
undetectable		 2vxaA-3muoA:
7.15
2vxaB-3muoA:
7.15
2vxaK-3muoA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLN A  58
TYR A 679
HIS A 645
GLN A 647
 None
SUC  A 703 (-3.9A)
None
None
 1.19A 2vxaD-3muoA:
undetectable
2vxaE-3muoA:
undetectable
2vxaL-3muoA:
undetectable		 2vxaD-3muoA:
7.15
2vxaE-3muoA:
7.15
2vxaL-3muoA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 HIS A 645
GLN A 647
TYR A 679
GLN A  58
 None
None
SUC  A 703 (-3.9A)
None
 1.21A 2vxaF-3muoA:
undetectable
2vxaG-3muoA:
undetectable
2vxaI-3muoA:
undetectable		 2vxaF-3muoA:
7.15
2vxaG-3muoA:
7.15
2vxaI-3muoA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLN A  58
TYR A 679
HIS A 645
GLN A 647
 None
SUC  A 703 (-3.9A)
None
None
 1.18A 2vxaH-3muoA:
undetectable
2vxaI-3muoA:
undetectable
2vxaJ-3muoA:
undetectable		 2vxaH-3muoA:
7.15
2vxaI-3muoA:
7.15
2vxaJ-3muoA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 HIS A 645
GLN A 647
TYR A 679
GLN A  58
 None
None
SUC  A 703 (-3.9A)
None
 1.19A 2vxaD-3muoA:
undetectable
2vxaJ-3muoA:
undetectable
2vxaL-3muoA:
undetectable		 2vxaD-3muoA:
7.15
2vxaJ-3muoA:
7.15
2vxaL-3muoA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 HIS A 645
GLN A 647
GLN A  58
TYR A 679
 None
None
None
SUC  A 703 (-3.9A)
 1.19A 2vxaA-3muoA:
undetectable
2vxaK-3muoA:
undetectable
2vxaL-3muoA:
undetectable		 2vxaA-3muoA:
7.15
2vxaK-3muoA:
7.15
2vxaL-3muoA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 LEU A 263
VAL A 222
ILE A 247
PHE A 186
 None
 0.96A 2weyB-3muoA:
undetectable		 2weyB-3muoA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 SER A 149
ALA A 655
GLY A 660
THR A 661
LEU A 128
 None
 1.02A 2zifB-3muoA:
2.8		 2zifB-3muoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.28A 3bjmA-3muoA:
24.8		 3bjmA-3muoA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.32A 3bjmB-3muoA:
24.4		 3bjmB-3muoA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 ARG A 201
ASP A  19
GLN A  17
GLU A  34
 None
 0.97A 3dh0A-3muoA:
undetectable		 3dh0A-3muoA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		3 / 3 ASP A 623
SER A 149
ARG A 152
 None
 0.99A 3loqA-3muoA:
undetectable		 3loqA-3muoA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 4 GLY A 491
GLU A 493
ASP A 513
ASP A 462
 None
 1.38A 3mb5A-3muoA:
undetectable		 3mb5A-3muoA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLY A 502
ALA A 501
GLY A 492
PRO A 436
VAL A 435
 None
 1.02A 3ndxA-3muoA:
undetectable		 3ndxA-3muoA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 4 ASP A 623
ASP A 622
GLY A 148
THR A 653
 None
 1.27A 3tl9B-3muoA:
undetectable		 3tl9B-3muoA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 LEU A 686
GLY A 481
TYR A 483
ALA A 533
LEU A 559
 None
None
ZPR  A 702 (-4.8A)
None
None
 1.23A 3tm4A-3muoA:
undetectable		 3tm4A-3muoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 LEU A 686
GLY A 481
TYR A 483
ALA A 533
LEU A 559
 None
None
ZPR  A 702 (-4.8A)
None
None
 1.24A 3tm4B-3muoA:
undetectable		 3tm4B-3muoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLY A 333
SER A 334
TYR A 336
GLU A 399
 None
 0.75A 3u9hA-3muoA:
undetectable		 3u9hA-3muoA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLY A 333
SER A 334
TYR A 336
GLU A 399
 None
 0.74A 3u9hB-3muoA:
undetectable		 3u9hB-3muoA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB502_1
(CYTOCHROME P450 2B6)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 10 GLN A 638
LEU A   7
GLU A 680
PHE A 676
VAL A 616
 None
 1.46A 3ua5B-3muoA:
1.2		 3ua5B-3muoA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.20A 3w2tA-3muoA:
25.8		 3w2tA-3muoA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.21A 3w2tB-3muoA:
25.7		 3w2tB-3muoA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLN A 274
GLY A 255
ALA A 279
GLN A 496
ASN A 296
 None
 1.24A 4azwA-3muoA:
undetectable		 4azwA-3muoA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLY A 333
SER A 334
TYR A 336
GLU A 399
 None
 0.72A 4bjcA-3muoA:
undetectable		 4bjcA-3muoA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 TRP A  32
GLU A  42
GLU A  40
ARG A  13
 None
None
None
SO4  A 801 (-2.8A)
 0.93A 4bqfB-3muoA:
5.1		 4bqfB-3muoA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.44A 4ffwA-3muoA:
25.6		 4ffwA-3muoA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.38A 4ffwB-3muoA:
23.3		 4ffwB-3muoA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 8 GLY A 356
GLU A 355
TYR A 292
LEU A 320
 None
 0.89A 4fgzB-3muoA:
2.4		 4fgzB-3muoA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLY A 502
ALA A 501
GLY A 492
PRO A 436
VAL A 435
 None
 1.03A 4hlaA-3muoA:
undetectable		 4hlaA-3muoA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 11 GLY A 502
ALA A 501
GLY A 492
PRO A 436
VAL A 435
 None
 1.02A 4hlaB-3muoA:
undetectable		 4hlaB-3muoA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 389
SER A 440
THR A 346
ALA A 345
ASN A 487
 None
 1.46A 4u15B-3muoA:
undetectable		 4u15B-3muoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 5 GLY A 213
THR A 214
GLY A 184
GLU A 166
 None
 0.94A 4v20A-3muoA:
undetectable		 4v20A-3muoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 6 PHE A 114
LEU A 128
PRO A 117
ARG A 104
 None
 1.45A 4yv5A-3muoA:
undetectable		 4yv5A-3muoA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		4 / 6 GLU A 387
GLY A 540
ARG A 535
GLY A 457
 None
None
ZPR  A 702 (-4.1A)
None
 0.91A 5cdpA-3muoA:
undetectable
5cdpB-3muoA:
3.6		 5cdpA-3muoA:
21.13
5cdpB-3muoA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 TYR A 458
SER A 538
VAL A 564
VAL A 625
HIS A 657
 ZPR  A 701 (-4.4A)
ZPR  A 701 (-1.2A)
None
ZPR  A 701 (-4.9A)
ZPR  A 702 (-4.0A)
 0.22A 6b1eB-3muoA:
25.0		 6b1eB-3muoA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLU A 493
VAL A 547
PHE A 514
ILE A 515
PHE A 511
 None
 1.31A 6becA-3muoA:
undetectable
6becB-3muoA:
undetectable
6becC-3muoA:
undetectable		 6becA-3muoA:
21.37
6becB-3muoA:
21.37
6becC-3muoA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3muo PROLYL ENDOPEPTIDASE
(Aeromonas
caviae) 		5 / 12 GLY A 502
ALA A 501
GLY A 492
PRO A 436
VAL A 435
 None
 0.93A 6dh0B-3muoA:
undetectable		 6dh0B-3muoA:
8.08