SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3muq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  47
LEU A  46
GLN A 251
LEU A  31
MET A  81
 None
 1.28A 1a28B-3muqA:
undetectable		 1a28B-3muqA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 GLU A  73
PRO A 227
ARG A 229
GLY A  72
 None
 1.21A 2hs1B-3muqA:
undetectable		 2hs1B-3muqA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  47
LEU A  46
GLN A 251
LEU A  31
MET A  81
 None
 1.33A 3d90B-3muqA:
undetectable		 3d90B-3muqA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 GLU A  88
GLY A  89
THR A  90
GLU A  93
 None
 1.18A 3e9xA-3muqA:
5.5		 3e9xA-3muqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 SER A 147
GLY A 148
THR A 149
 None
 0.19A 3k9wA-3muqA:
undetectable		 3k9wA-3muqA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 ASP A 128
SER A 125
THR A 160
GLN A 159
ASP A 213
 None
 1.29A 3mbhE-3muqA:
undetectable		 3mbhE-3muqA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  77
ALA A  68
THR A  82
ILE A 223
PHE A  91
 None
 1.48A 3t3qA-3muqA:
undetectable		 3t3qA-3muqA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  77
ALA A  68
THR A  82
ILE A 223
PHE A  91
 None
 1.48A 3t3qB-3muqA:
undetectable		 3t3qB-3muqA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  77
ALA A  68
THR A  82
ILE A 223
PHE A  91
 None
 1.48A 3t3qC-3muqA:
undetectable		 3t3qC-3muqA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  77
ALA A  68
THR A  82
ILE A 223
PHE A  91
 None
 1.47A 3t3qD-3muqA:
undetectable		 3t3qD-3muqA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  43
ILE A 254
GLN A 251
VAL A  77
VAL A 222
 None
 1.27A 3w1wB-3muqA:
undetectable		 3w1wB-3muqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 PHE A  91
TYR A  96
VAL A 225
ILE A 233
 None
 1.13A 4a97H-3muqA:
undetectable		 4a97H-3muqA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 PHE A  91
TYR A  96
VAL A 225
ILE A 233
 None
 1.10A 4a97I-3muqA:
undetectable		 4a97I-3muqA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 6 THR A 190
ILE A 110
THR A 160
PHE A 156
 None
 1.05A 4acbC-3muqA:
undetectable		 4acbC-3muqA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 PRO A 164
SER A 142
TRP A 157
HIS A 150
 None
 1.17A 4k7gB-3muqA:
undetectable		 4k7gB-3muqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 PRO A 164
SER A 171
TRP A 157
HIS A 150
 None
 0.96A 4k7gB-3muqA:
undetectable		 4k7gB-3muqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ASN A 135
PHE A 130
TYR A 189
 None
 0.76A 4u15A-3muqA:
undetectable		 4u15A-3muqA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 GLY A 188
ALA A 183
GLY A 112
PRO A 113
 None
 0.84A 4u9uA-3muqA:
undetectable		 4u9uA-3muqA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 GLY A 188
ALA A 183
GLY A 112
PRO A 113
 None
 0.86A 4u9uB-3muqA:
undetectable		 4u9uB-3muqA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 ALA A 183
PHE A 140
LEU A 180
VAL A 172
GLY A 144
 None
 1.13A 5x24A-3muqA:
undetectable		 5x24A-3muqA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3muq UNCHARACTERIZED
CONSERVED PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 VAL A  80
LEU A  79
LEU A 224
ASP A 243
 None
 1.45A 5xv7A-3muqA:
undetectable		 5xv7A-3muqA:
17.81