SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3muu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 VAL A 312
THR A 289
GLU A 138
LEU A 292
None
1.07A 1s8fB-3muuA:
undetectable
1s8fB-3muuA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.75A 1v54N-3muuA:
undetectable
1v54W-3muuA:
undetectable
1v54N-3muuA:
21.45
1v54W-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.72A 1v55A-3muuA:
undetectable
1v55J-3muuA:
undetectable
1v55A-3muuA:
21.45
1v55J-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.76A 2dyrN-3muuA:
undetectable
2dyrW-3muuA:
undetectable
2dyrN-3muuA:
21.45
2dyrW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.74A 2eijN-3muuA:
undetectable
2eijW-3muuA:
undetectable
2eijN-3muuA:
21.45
2eijW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.74A 2eikN-3muuA:
undetectable
2eikW-3muuA:
undetectable
2eikN-3muuA:
21.45
2eikW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.68A 2einN-3muuA:
undetectable
2einW-3muuA:
undetectable
2einN-3muuA:
21.45
2einW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 SER A 516
ILE A 495
SER A 502
THR A 365
PRO A 643
None
1.04A 2nnhA-3muuA:
undetectable
2nnhA-3muuA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.82A 3abkA-3muuA:
undetectable
3abkJ-3muuA:
undetectable
3abkA-3muuA:
21.45
3abkJ-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.73A 3ablN-3muuA:
undetectable
3ablW-3muuA:
undetectable
3ablN-3muuA:
21.45
3ablW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.87A 3ag1N-3muuA:
undetectable
3ag1W-3muuA:
undetectable
3ag1N-3muuA:
21.45
3ag1W-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.72A 3ag3A-3muuA:
undetectable
3ag3J-3muuA:
undetectable
3ag3A-3muuA:
21.45
3ag3J-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 VAL A 484
THR A 402
ILE A 482
ILE A 539
None
0.83A 3deuA-3muuA:
undetectable
3deuA-3muuA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 9 ILE A 642
TYR A 361
ILE A 640
LEU A 389
LEU A 387
None
1.06A 3f78A-3muuA:
undetectable
3f78A-3muuA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 9 ILE A 642
TYR A 361
ILE A 640
LEU A 389
LEU A 387
None
1.04A 3f78B-3muuA:
undetectable
3f78B-3muuA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.86A 3wg7N-3muuA:
undetectable
3wg7W-3muuA:
undetectable
3wg7N-3muuA:
21.45
3wg7W-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 4 ALA A  38
VAL A 154
ASP A  40
LEU A 102
None
1.41A 4e7gA-3muuA:
undetectable
4e7gA-3muuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 VAL A 521
SER A 502
ALA A 646
PHE A 647
None
1.11A 4nedA-3muuA:
undetectable
4nedA-3muuA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 LEU A 101
ASP A  36
VAL A  34
THR A  47
ILE A  45
None
0.91A 4njtA-3muuA:
undetectable
4njtA-3muuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 LEU A 101
ASP A  36
VAL A  34
THR A  47
ILE A  45
None
0.86A 4njtC-3muuA:
undetectable
4njtC-3muuA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 5 TYR A 339
ARG A 337
ASP A 630
VAL A 367
None
1.42A 4nkvB-3muuA:
undetectable
4nkvB-3muuA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 4 SER A 632
GLU A 327
GLU A 334
ASP A 630
None
1.43A 4pclB-3muuA:
undetectable
4pclB-3muuA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qvlV-3muuA:
undetectable
4qvlb-3muuA:
undetectable
4qvlV-3muuA:
16.39
4qvlb-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qvlH-3muuA:
undetectable
4qvlN-3muuA:
undetectable
4qvlH-3muuA:
16.39
4qvlN-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qvmV-3muuA:
undetectable
4qvmb-3muuA:
undetectable
4qvmV-3muuA:
16.39
4qvmb-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.40A 4qvmH-3muuA:
undetectable
4qvmN-3muuA:
undetectable
4qvmH-3muuA:
16.39
4qvmN-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qvpV-3muuA:
undetectable
4qvpb-3muuA:
undetectable
4qvpV-3muuA:
16.39
4qvpb-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.40A 4qvpH-3muuA:
undetectable
4qvpN-3muuA:
undetectable
4qvpH-3muuA:
16.39
4qvpN-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qvqV-3muuA:
undetectable
4qvqb-3muuA:
undetectable
4qvqV-3muuA:
16.39
4qvqb-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qvqH-3muuA:
undetectable
4qvqN-3muuA:
undetectable
4qvqH-3muuA:
16.39
4qvqN-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.40A 4qvwV-3muuA:
undetectable
4qvwb-3muuA:
undetectable
4qvwV-3muuA:
16.39
4qvwb-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qw1V-3muuA:
undetectable
4qw1b-3muuA:
undetectable
4qw1V-3muuA:
16.39
4qw1b-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qw1H-3muuA:
undetectable
4qw1N-3muuA:
undetectable
4qw1H-3muuA:
16.39
4qw1N-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 4qw3H-3muuA:
undetectable
4qw3N-3muuA:
undetectable
4qw3H-3muuA:
16.39
4qw3N-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 LEU A 101
ASP A  36
VAL A  34
THR A  47
ILE A  45
None
0.91A 4rvjA-3muuA:
undetectable
4rvjA-3muuA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 LEU A 101
ASP A  36
VAL A  34
THR A  47
ILE A  45
None
0.91A 4rvjC-3muuA:
undetectable
4rvjC-3muuA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 12 HIS A 291
THR A 289
GLU A 138
GLY A 331
GLY A 147
None
0.91A 4uinH-3muuA:
4.4
4uinL-3muuA:
3.2
4uinH-3muuA:
16.51
4uinL-3muuA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.86A 5b1bA-3muuA:
undetectable
5b1bJ-3muuA:
undetectable
5b1bA-3muuA:
21.45
5b1bJ-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.91A 5b1bN-3muuA:
undetectable
5b1bW-3muuA:
undetectable
5b1bN-3muuA:
21.45
5b1bW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.77A 5b3sN-3muuA:
undetectable
5b3sW-3muuA:
undetectable
5b3sN-3muuA:
21.45
5b3sW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.42A 5bxnV-3muuA:
undetectable
5bxnb-3muuA:
undetectable
5bxnV-3muuA:
16.53
5bxnb-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.42A 5bxnH-3muuA:
undetectable
5bxnN-3muuA:
undetectable
5bxnH-3muuA:
16.53
5bxnN-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.77A 5iy5A-3muuA:
undetectable
5iy5J-3muuA:
undetectable
5iy5A-3muuA:
21.45
5iy5J-3muuA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.75A 5iy5N-3muuA:
undetectable
5iy5W-3muuA:
undetectable
5iy5N-3muuA:
21.45
5iy5W-3muuA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 5l66V-3muuA:
undetectable
5l66b-3muuA:
undetectable
5l66V-3muuA:
16.39
5l66b-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 11 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.41A 5l66H-3muuA:
undetectable
5l66N-3muuA:
undetectable
5l66H-3muuA:
16.39
5l66N-3muuA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 12 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.40A 5lf3b-3muuA:
undetectable
5lf3b-3muuA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 12 THR A 413
THR A 412
GLY A 435
ALA A 466
THR A 437
None
1.40A 5lf3N-3muuA:
undetectable
5lf3N-3muuA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
3 / 3 VAL A  75
LYS A  63
MET A  80
None
0.97A 5nknA-3muuA:
undetectable
5nknA-3muuA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.95A 5xdqA-3muuA:
undetectable
5xdqJ-3muuA:
undetectable
5xdqA-3muuA:
21.45
5xdqJ-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.75A 5xdqN-3muuA:
undetectable
5xdqW-3muuA:
undetectable
5xdqN-3muuA:
21.45
5xdqW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.75A 5xdxA-3muuA:
undetectable
5xdxJ-3muuA:
undetectable
5xdxA-3muuA:
21.45
5xdxJ-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.77A 5xdxN-3muuA:
undetectable
5xdxW-3muuA:
undetectable
5xdxN-3muuA:
21.45
5xdxW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
5 / 12 GLU A 327
VAL A 336
GLU A 138
HIS A 291
GLY A 136
None
1.30A 5xioA-3muuA:
undetectable
5xioA-3muuA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.76A 5z86N-3muuA:
undetectable
5z86W-3muuA:
undetectable
5z86N-3muuA:
21.45
5z86W-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 6 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.79A 5zcoN-3muuA:
undetectable
5zcoW-3muuA:
undetectable
5zcoN-3muuA:
21.45
5zcoW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.77A 5zcpN-3muuA:
undetectable
5zcpW-3muuA:
undetectable
5zcpN-3muuA:
21.45
5zcpW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 8 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.93A 5zcqN-3muuA:
undetectable
5zcqW-3muuA:
undetectable
5zcqN-3muuA:
21.45
5zcqW-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 7 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.84A 6nmpA-3muuA:
undetectable
6nmpJ-3muuA:
undetectable
6nmpA-3muuA:
21.45
6nmpJ-3muuA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3muu STRUCTURAL
POLYPROTEIN

(Sindbis
virus)
4 / 5 ILE A 283
ARG A 298
THR A 296
LEU A 295
None
0.74A 6nmpN-3muuA:
undetectable
6nmpW-3muuA:
undetectable
6nmpN-3muuA:
21.45
6nmpW-3muuA:
6.16