SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 3mv3 COATOMER SUBUNIT
ALPHA
COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 THR A 957
GLY B  13
LYS B  39
TYR B  10
 None
 1.20A 1gtiC-3mv3A:
undetectable		 1gtiC-3mv3A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		5 / 12 ASP B  30
GLY B 120
TYR B  87
GLU B 117
TYR B   3
 None
 1.35A 1maaA-3mv3B:
undetectable		 1maaA-3mv3B:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 5 GLU B 130
LEU B 124
LEU B 127
LEU B 125
 None
 0.93A 1np1A-3mv3B:
undetectable		 1np1A-3mv3B:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 4 THR B  29
GLY B  57
ASP B  61
ALA B  38
 None
 1.25A 1sg9A-3mv3B:
2.3		 1sg9A-3mv3B:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 900
ALA A 916
LEU A 914
VAL A 984
 None
 0.95A 1sn5C-3mv3A:
undetectable		 1sn5C-3mv3A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 THR A1073
PRO A1143
TYR A1104
 None
 0.89A 2dxrA-3mv3A:
undetectable		 2dxrA-3mv3A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 8 LEU A1038
LEU A1022
VAL A 933
GLY A 932
 None
 0.96A 2po5A-3mv3A:
undetectable		 2po5A-3mv3A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 6 GLU A1043
MET A 994
PHE A1013
ILE A1017
 None
 1.44A 2w98B-3mv3A:
undetectable		 2w98B-3mv3A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 ASN A1098
ALA A1070
ALA A1069
ALA A1089
 None
 0.89A 3a2qA-3mv3A:
undetectable		 3a2qA-3mv3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		5 / 11 ASN B 235
VAL B  16
CYH B  18
TYR B  36
TYR B 239
 None
 1.48A 3bgrA-3mv3B:
undetectable
3bgrB-3mv3B:
undetectable		 3bgrA-3mv3B:
21.42
3bgrB-3mv3B:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 951
GLU A 900
THR A 901
 None
 0.70A 3v4tA-3mv3A:
undetectable		 3v4tA-3mv3A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 4 LEU B 133
ALA B 167
PHE B 145
ASN B 183
 None
 1.27A 3vaqA-3mv3B:
undetectable		 3vaqA-3mv3B:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 4 LEU B 133
ALA B 167
PHE B 145
ASN B 183
 None
 1.27A 3vasA-3mv3B:
undetectable		 3vasA-3mv3B:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 932
ILE A1187
ILE A1017
LEU A1038
ASP A1166
 None
 1.02A 4dt8A-3mv3A:
undetectable		 4dt8A-3mv3A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3mv3 COATOMER SUBUNIT
ALPHA
COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 PRO A 958
ILE B 163
TYR B  10
TYR B  36
 None
 1.03A 4g10A-3mv3A:
undetectable		 4g10A-3mv3A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 7 THR B 258
LEU B 224
GLN B 200
LEU B 204
 None
 1.04A 4ib4A-3mv3B:
undetectable		 4ib4A-3mv3B:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 3mv3 COATOMER SUBUNIT
ALPHA
COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 971
THR A1021
LEU A1022
MET B 253
 None
 1.46A 4mbsB-3mv3A:
undetectable		 4mbsB-3mv3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3mv3 COATOMER SUBUNIT
ALPHA
COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 8 LEU B 256
GLY B 255
GLU A1015
ALA A1016
 None
 0.88A 4rjdA-3mv3B:
undetectable
4rjdB-3mv3B:
undetectable		 4rjdA-3mv3B:
12.46
4rjdB-3mv3B:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3mv3 COATOMER SUBUNIT
ALPHA
COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 ASN B 136
ARG A 951
GLY A 918
ALA A 917
TRP A 904
 None
 1.44A 4ryaA-3mv3B:
undetectable		 4ryaA-3mv3B:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 SER A1188
GLU A1177
GLU A1053
 None
 0.70A 4ymgB-3mv3A:
undetectable		 4ymgB-3mv3A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 7 LEU B 204
ALA B 216
LEU B 208
ALA B 251
 None
 0.66A 4z90F-3mv3B:
3.5
4z90G-3mv3B:
3.5
4z90H-3mv3B:
3.6
4z90J-3mv3B:
3.4		 4z90F-3mv3B:
22.70
4z90G-3mv3B:
22.70
4z90H-3mv3B:
22.70
4z90J-3mv3B:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 7 LEU B  91
TYR B  90
THR B 122
LEU B  60
 None
 0.84A 5jq7B-3mv3B:
undetectable		 5jq7B-3mv3B:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 8 THR B 199
ASN B 235
TYR B 239
PHE B  15
 None
 1.27A 5v4vA-3mv3B:
undetectable		 5v4vA-3mv3B:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		4 / 8 THR B 199
ASN B 235
TYR B 239
PHE B  15
 None
 1.25A 5v4vB-3mv3B:
undetectable		 5v4vB-3mv3B:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 THR A1169
ASP A1166
LEU A1168
TYR A1018
 None
 1.04A 5zsfA-3mv3A:
undetectable
5zsfB-3mv3A:
undetectable		 5zsfA-3mv3A:
13.88
5zsfB-3mv3A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 987
GLY A 986
LEU A 914
VAL A 915
ILE A 946
 None
 1.11A 6bxmA-3mv3A:
undetectable		 6bxmA-3mv3A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3mv3 COATOMER SUBUNIT
ALPHA
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 987
VAL A1025
LEU A1197
GLU A1031
ILE A1199
 None
 1.32A 6fdyU-3mv3A:
undetectable		 6fdyU-3mv3A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3mv3 COATOMER SUBUNIT
EPSILON
(Saccharomyces
cerevisiae) 		3 / 3 ASP B  51
ASP B  30
ASN B 160
 None
 0.83A 6gngB-3mv3B:
undetectable		 6gngB-3mv3B:
19.42