SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 8 ARG A 313
GLU A 316
GLN A 328
HIS A 211
 None
 1.15A 1nx9A-3mvcA:
undetectable		 1nx9A-3mvcA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 8 ARG A 313
GLU A 316
GLN A 328
HIS A 211
 None
 1.15A 1nx9B-3mvcA:
undetectable		 1nx9B-3mvcA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 8 ARG A 313
GLU A 316
GLN A 328
HIS A 211
 None
 1.15A 1nx9C-3mvcA:
undetectable		 1nx9C-3mvcA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 8 ARG A 313
GLU A 316
GLN A 328
HIS A 211
 None
 1.15A 1nx9D-3mvcA:
undetectable		 1nx9D-3mvcA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 8 PHE A 225
ALA A 282
HIS A 286
LEU A 303
 None
HEM  A 500 ( 4.0A)
HEM  A 500 (-3.2A)
HEM  A 500 (-4.6A)
 1.15A 1x8vA-3mvcA:
1.6		 1x8vA-3mvcA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 6 PHE A 306
THR A 339
VAL A 338
LEU A 279
 HEM  A 500 ( 4.1A)
None
None
None
 0.98A 2e1qA-3mvcA:
2.7		 2e1qA-3mvcA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		4 / 6 PHE A 306
THR A 339
VAL A 338
LEU A 279
 HEM  A 500 ( 4.1A)
None
None
None
 0.93A 2e1qC-3mvcA:
undetectable		 2e1qC-3mvcA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3mvc GLOBIN PROTEIN 6
(Caenorhabditis
elegans) 		5 / 12 VAL A 260
LEU A 265
VAL A 338
LEU A 342
PHE A 337
 None
None
None
HEM  A 500 ( 4.8A)
None
 1.14A 3w68A-3mvcA:
undetectable		 3w68A-3mvcA:
18.12