SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		4 / 7 THR K 110
SER K 111
SER K  97
LEU K  87
 None
 1.08A 1ibgL-3mvdK:
undetectable		 1ibgL-3mvdK:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 TYR K 251
GLY K 301
VAL K 355
ALA K 248
GLY K 408
 None
 1.07A 1nbiA-3mvdK:
undetectable		 1nbiA-3mvdK:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 TYR K 251
GLY K 301
VAL K 355
ALA K 248
GLY K 408
 None
 1.07A 1nbiB-3mvdK:
undetectable		 1nbiB-3mvdK:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 TYR K 358
GLY K  83
ASN K  86
LEU K 366
VAL K 360
 None
 1.23A 1r30A-3mvdK:
undetectable		 1r30A-3mvdK:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		4 / 8 ALA K 265
ILE K 288
GLY K 211
HIS K 189
 None
 0.80A 1sv9A-3mvdK:
undetectable		 1sv9A-3mvdK:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 PHE K 413
ALA K  81
SER K  80
ALA K 411
GLY K 351
 None
 1.14A 2igtA-3mvdK:
undetectable		 2igtA-3mvdK:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 9 ILE K 412
GLY K 406
GLY K 353
SER K 132
SER K 138
 None
 1.19A 2qmmA-3mvdK:
undetectable		 2qmmA-3mvdK:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		3 / 3 LEU K 402
VAL K  88
ARG K  38
 None
 0.87A 3b0wB-3mvdK:
undetectable		 3b0wB-3mvdK:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		4 / 6 THR K 305
VAL K 306
CYH K 352
SER K 357
 None
 1.16A 3b6rB-3mvdK:
undetectable		 3b6rB-3mvdK:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 ALA K 411
GLY K  48
LEU K  45
SER K  68
LEU K 366
 None
 1.38A 3bxoA-3mvdK:
undetectable		 3bxoA-3mvdK:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  42
ASP K 418
ILE K  73
GLY K  72
LEU K 414
 None
 1.09A 3eeyD-3mvdK:
undetectable		 3eeyD-3mvdK:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 ALA K 139
GLY K 186
ILE K 131
LEU K  87
SER K  80
 None
 1.28A 3gyqA-3mvdK:
undetectable
3gyqB-3mvdK:
undetectable		 3gyqA-3mvdK:
23.37
3gyqB-3mvdK:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  83
GLY K  82
ASN K 374
GLY K 372
LEU K 377
 None
 0.98A 4fp9A-3mvdK:
undetectable		 4fp9A-3mvdK:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  83
GLY K  82
ASN K 374
GLY K 372
LEU K 377
 None
 1.01A 4fp9C-3mvdK:
undetectable		 4fp9C-3mvdK:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  83
GLY K  82
ASN K 374
GLY K 372
LEU K 377
 None
 0.99A 4fp9D-3mvdK:
undetectable		 4fp9D-3mvdK:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  83
GLY K  82
ASN K 374
GLY K 372
LEU K 377
 None
 0.97A 4fp9F-3mvdK:
undetectable		 4fp9F-3mvdK:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  83
GLY K  82
ASN K 374
GLY K 372
LEU K 377
 None
 1.00A 4fzvA-3mvdK:
undetectable		 4fzvA-3mvdK:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 11 ILE K 246
ALA K 248
LEU K 190
LEU K 141
THR K 253
 None
 1.21A 4i1nA-3mvdK:
undetectable		 4i1nA-3mvdK:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 ILE K 246
ALA K 248
LEU K 190
LEU K 141
THR K 253
 None
 1.19A 4qlgA-3mvdK:
undetectable		 4qlgA-3mvdK:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 ILE K 246
ALA K 248
LEU K 190
LEU K 141
THR K 253
 None
 1.19A 4rgcA-3mvdK:
undetectable		 4rgcA-3mvdK:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		4 / 6 GLY K 114
GLU K  59
ASP K 120
ASP K 113
 None
 1.01A 4uckB-3mvdK:
undetectable		 4uckB-3mvdK:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 TRP K 150
SER K 132
GLY K 151
GLY K 203
LEU K 190
 None
 1.35A 4uinH-3mvdK:
undetectable
4uinL-3mvdK:
undetectable		 4uinH-3mvdK:
19.42
4uinL-3mvdK:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		3 / 3 ASN K 159
SER K 152
ARG K 169
 None
 0.93A 5b2qA-3mvdK:
undetectable		 5b2qA-3mvdK:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		3 / 3 ASN K 167
SER K 152
ARG K 154
 None
 0.59A 5b2qA-3mvdK:
undetectable		 5b2qA-3mvdK:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 LEU K 190
ILE K 298
THR K 249
GLY K 300
GLY K 134
 None
 1.08A 5d4uA-3mvdK:
undetectable		 5d4uA-3mvdK:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 LEU K 190
ILE K 298
THR K 249
GLY K 300
GLY K 134
 None
 1.08A 5d4uB-3mvdK:
undetectable		 5d4uB-3mvdK:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K 301
GLY K 353
VAL K 306
ALA K 299
ALA K 248
 None
 0.90A 5kpcA-3mvdK:
undetectable		 5kpcA-3mvdK:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		4 / 7 GLN K 409
GLY K  83
GLN K 207
ASP K 188
 None
 1.15A 5vlmE-3mvdK:
undetectable		 5vlmE-3mvdK:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		5 / 12 GLY K  99
GLY K  56
ILE K 122
VAL K  88
LEU K  87
 None
 0.91A 5wyqA-3mvdK:
undetectable		 5wyqA-3mvdK:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 3mvd REGULATOR OF
CHROMOSOME
CONDENSATION
(Drosophila
melanogaster) 		4 / 6 LEU K 174
ALA K 149
LEU K 230
ASN K 159
 None
 0.94A 6f88B-3mvdK:
undetectable		 6f88B-3mvdK:
9.93