SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 9 GLY A 106
TYR A 108
ILE A 156
GLU A 161
ARG A 164
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
 0.55A 1mrgA-3mvgA:
32.6		 1mrgA-3mvgA:
33.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 8 GLY A 106
TYR A 108
ILE A 156
GLU A 161
ARG A 164
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
 0.45A 1mrjA-3mvgA:
32.4		 1mrjA-3mvgA:
32.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 8 GLY A 106
TYR A 108
ILE A 156
SER A 160
GLU A 161
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
None
 0.28A 1mrjA-3mvgA:
32.4		 1mrjA-3mvgA:
32.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		3 / 3 LEU A 247
LEU A  38
SER A  29
 None
None
SO4  A 276 ( 4.8A)
 0.63A 1tlmA-3mvgA:
undetectable		 1tlmA-3mvgA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		6 / 9 ALA A 115
VAL A 114
GLY A 109
ILE A 156
LEU A 152
ALA A 149
 None
None
GOL  A 281 (-3.6A)
None
None
None
 1.34A 2z0yA-3mvgA:
undetectable		 2z0yA-3mvgA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		4 / 7 VAL A 172
THR A 173
ILE A 176
SER A  15
 None
None
None
GOL  A 285 (-4.2A)
 0.86A 3deuA-3mvgA:
undetectable		 3deuA-3mvgA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		3 / 3 SER A  29
GLY A  30
THR A  31
 SO4  A 276 ( 4.8A)
GOL  A 277 ( 3.7A)
None
 0.23A 3k9wA-3mvgA:
undetectable		 3k9wA-3mvgA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 6 ALA A 167
ILE A 194
LEU A 197
GLU A 169
ALA A 245
 GOL  A 280 ( 4.0A)
None
GOL  A 280 ( 4.0A)
None
None
 1.45A 3r9sA-3mvgA:
undetectable		 3r9sA-3mvgA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 11 LEU A  39
SER A 205
LEU A 204
PHE A 165
ALA A  71
 None
 1.40A 4hwkB-3mvgA:
undetectable		 4hwkB-3mvgA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 12 LEU A  39
SER A 205
LEU A 204
PHE A 165
ALA A  71
 None
 1.39A 4hwkC-3mvgA:
undetectable		 4hwkC-3mvgA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 11 LEU A  39
SER A 205
LEU A 204
PHE A 165
ALA A  71
 None
 1.40A 4hwkD-3mvgA:
undetectable		 4hwkD-3mvgA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 12 ILE A 156
LEU A 129
ILE A  62
LEU A 136
THR A 162
 None
 1.17A 4qlgA-3mvgA:
undetectable		 4qlgA-3mvgA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		3 / 3 ASP A  48
ARG A 249
PRO A  40
 None
None
SO4  A 276 (-4.1A)
 1.00A 4wanC-3mvgA:
undetectable		 4wanC-3mvgA:
20.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 9 GLY A 106
TYR A 108
ILE A 156
GLU A 161
ARG A 164
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
 0.50A 4yp2B-3mvgA:
25.3		 4yp2B-3mvgA:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 9 GLY A 106
TYR A 108
ILE A 156
GLU A 161
ARG A 164
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
 0.50A 5cf9B-3mvgA:
32.8		 5cf9B-3mvgA:
32.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 6 VAL A  73
TYR A 108
ILE A 156
GLU A 161
ARG A 164
 None
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
 0.38A 5z3jA-3mvgA:
32.7		 5z3jA-3mvgA:
31.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN
(Iris
x
hollandica) 		5 / 12 VAL A 172
THR A 173
LEU A 155
PHE A   6
VAL A   8
 None
 1.30A 6a93B-3mvgA:
undetectable		 6a93B-3mvgA:
22.47