SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		5 / 12 MET A  20
VAL A  16
LEU A  17
VAL A  27
ALA A 122
 None
 0.96A 1epbA-3mvkA:
undetectable		 1epbA-3mvkA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		5 / 11 LEU A  60
LEU A  17
LYS A 141
LEU A 139
ILE A  28
 None
 1.10A 4x20D-3mvkA:
undetectable		 4x20D-3mvkA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		5 / 8 ALA A 106
LEU A  65
LEU A  60
LEU A  56
LEU A 137
 None
 0.73A 4z90A-3mvkA:
undetectable
4z90B-3mvkA:
undetectable
4z90C-3mvkA:
undetectable
4z90D-3mvkA:
undetectable
4z90E-3mvkA:
undetectable		 4z90A-3mvkA:
19.12
4z90B-3mvkA:
19.12
4z90C-3mvkA:
19.12
4z90D-3mvkA:
19.12
4z90E-3mvkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		5 / 8 LEU A  56
LEU A 137
ALA A 106
LEU A  65
LEU A  60
 None
 0.72A 4z90A-3mvkA:
undetectable
4z90B-3mvkA:
undetectable
4z90C-3mvkA:
undetectable
4z90D-3mvkA:
undetectable
4z90E-3mvkA:
undetectable		 4z90A-3mvkA:
19.12
4z90B-3mvkA:
19.12
4z90C-3mvkA:
19.12
4z90D-3mvkA:
19.12
4z90E-3mvkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		5 / 8 LEU A  65
LEU A  60
LEU A  56
LEU A 137
ALA A 106
 None
 0.69A 4z90A-3mvkA:
undetectable
4z90B-3mvkA:
undetectable
4z90C-3mvkA:
undetectable
4z90D-3mvkA:
undetectable
4z90E-3mvkA:
undetectable		 4z90A-3mvkA:
19.12
4z90B-3mvkA:
19.12
4z90C-3mvkA:
19.12
4z90D-3mvkA:
19.12
4z90E-3mvkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		4 / 7 LEU A  56
LEU A 137
ALA A 106
LEU A  60
 None
 0.57A 4z90F-3mvkA:
undetectable
4z90G-3mvkA:
undetectable
4z90H-3mvkA:
undetectable
4z90J-3mvkA:
undetectable		 4z90F-3mvkA:
19.12
4z90G-3mvkA:
19.12
4z90H-3mvkA:
19.12
4z90J-3mvkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		3 / 3 GLY A  21
ASP A  24
ASN A 121
 None
PGE  A 151 (-4.3A)
None
 0.60A 5jglA-3mvkA:
2.3		 5jglA-3mvkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		4 / 6 PHE A  33
LEU A 137
SER A 128
GLY A  52
 None
 1.14A 5o4yF-3mvkA:
undetectable		 5o4yF-3mvkA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3mvk PROTEIN FUCU
(Bifidobacterium
longum) 		5 / 9 LEU A  13
ILE A  59
PRO A   6
VAL A  62
ILE A   9
 None
 1.28A 6ef6A-3mvkA:
undetectable		 6ef6A-3mvkA:
17.97