SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RCT_A_RTLA140_0 (RETINOL-BINDING PROTEIN II, CELLULAR)	3mvn	UDP-N-ACETYLMURAMATE :L-ALANYL-GAMMA-D-GL UTAMYL-MEDO-DIAMINOP IMELATE LIGASE ([Haemophilus] ducreyi)	5 / 12	ILE A 344 ALA A 334 VAL A 398 LEU A 380 LEU A 418	None	1.39A	2rctA-3mvnA: undetectable	2rctA-3mvnA: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1476_0 (TRANSLATION ELONGATION FACTOR SELB)	3mvn	UDP-N-ACETYLMURAMATE :L-ALANYL-GAMMA-D-GL UTAMYL-MEDO-DIAMINOP IMELATE LIGASE ([Haemophilus] ducreyi)	4 / 5	ILE A 340 ALA A 358 HIS A 335 MET A 435	None	1.31A	4acaB-3mvnA: 4.1 4acaC-3mvnA: 3.9	4acaB-3mvnA: 16.14 4acaC-3mvnA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XYZ_A_ACTA103_0 (POLYUBIQUITIN-C)	3mvn	UDP-N-ACETYLMURAMATE :L-ALANYL-GAMMA-D-GL UTAMYL-MEDO-DIAMINOP IMELATE LIGASE ([Haemophilus] ducreyi)	4 / 4	LEU A 448 ILE A 434 HIS A 444 VAL A 329	None	1.19A	4xyzA-3mvnA: undetectable	4xyzA-3mvnA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_C_STRC603_1 (CYTOCHROME P450 21-HYDROXYLASE)	3mvn	UDP-N-ACETYLMURAMATE :L-ALANYL-GAMMA-D-GL UTAMYL-MEDO-DIAMINOP IMELATE LIGASE ([Haemophilus] ducreyi)	5 / 12	VAL A 329 ASP A 331 ILE A 432 ILE A 443 GLY A 441	None	1.02A	4y8wC-3mvnA: undetectable	4y8wC-3mvnA: 15.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2RCT_A_RTLA140_0","RETINOL-BINDING PROTEIN II, CELLULAR","3mvn","UDP-N-ACETYLMURAMATE:L-ALANYL-GAMMA-D-GLUTAMYL-MEDO-DIAMINOPIMELATE LIGASE","[Haemophilus] ducreyi",5,"ILE A 344;ALA A 334;VAL A 398;LEU A 380;LEU A 418","None","1.39A","2rctA-3mvnA:undetectable","2rctA-3mvnA:19.77"],["4ACA_C_DXCC1476_0","TRANSLATION ELONGATION FACTOR SELB","3mvn","UDP-N-ACETYLMURAMATE:L-ALANYL-GAMMA-D-GLUTAMYL-MEDO-DIAMINOPIMELATE LIGASE","[Haemophilus] ducreyi",4,"ILE A 340;ALA A 358;HIS A 335;MET A 435","None","1.31A","4acaB-3mvnA:4.1;4acaC-3mvnA:3.9","4acaB-3mvnA:16.14;4acaC-3mvnA:16.14"],["4XYZ_A_ACTA103_0","POLYUBIQUITIN-C","3mvn","UDP-N-ACETYLMURAMATE:L-ALANYL-GAMMA-D-GLUTAMYL-MEDO-DIAMINOPIMELATE LIGASE","[Haemophilus] ducreyi",4,"LEU A 448;ILE A 434;HIS A 444;VAL A 329","None","1.19A","4xyzA-3mvnA:undetectable","4xyzA-3mvnA:18.30"],["4Y8W_C_STRC603_1","CYTOCHROME P450 21-HYDROXYLASE","3mvn","UDP-N-ACETYLMURAMATE:L-ALANYL-GAMMA-D-GLUTAMYL-MEDO-DIAMINOPIMELATE LIGASE","[Haemophilus] ducreyi",5,"VAL A 329;ASP A 331;ILE A 432;ILE A 443;GLY A 441","None","1.02A","4y8wC-3mvnA:undetectable","4y8wC-3mvnA:15.89"]]