SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 3mvp TETR/ACRR
TRANSCRIPTIONAL
REGULATOR
(Streptococcus
mutans) 		5 / 12 LEU A  32
LEU A  74
ALA A 133
ALA A 139
HIS A 126
 None
 1.28A 1rbpA-3mvpA:
undetectable		 1rbpA-3mvpA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3mvp TETR/ACRR
TRANSCRIPTIONAL
REGULATOR
(Streptococcus
mutans) 		5 / 12 LEU A  78
LEU A  32
ALA A  35
ILE A  52
ILE A 136
 None
 1.13A 1tw4A-3mvpA:
undetectable		 1tw4A-3mvpA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3mvp TETR/ACRR
TRANSCRIPTIONAL
REGULATOR
(Streptococcus
mutans) 		5 / 12 ALA A  35
ILE A  52
THR A  49
ILE A 136
LEU A 132
 None
 1.18A 2jn3A-3mvpA:
undetectable		 2jn3A-3mvpA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3mvp TETR/ACRR
TRANSCRIPTIONAL
REGULATOR
(Streptococcus
mutans) 		3 / 3 SER A  95
ASP A  92
ASP A 100
 None
 0.88A 3iv6C-3mvpA:
undetectable		 3iv6C-3mvpA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 3mvp TETR/ACRR
TRANSCRIPTIONAL
REGULATOR
(Streptococcus
mutans) 		3 / 3 SER A  69
ASP A  72
GLN A 138
 None
 0.94A 4oltA-3mvpA:
undetectable
4oltB-3mvpA:
undetectable		 4oltA-3mvpA:
20.86
4oltB-3mvpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3mvp TETR/ACRR
TRANSCRIPTIONAL
REGULATOR
(Streptococcus
mutans) 		3 / 3 GLN A 138
SER A  69
ASP A  72
 None
 0.95A 4qwpA-3mvpA:
undetectable
4qwpB-3mvpA:
undetectable		 4qwpA-3mvpA:
20.86
4qwpB-3mvpA:
20.86