SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UOB_A_PNNA1311_0 (DEACETOXYCEPHALOSPOR IN C SYNTHETASE)	3mvs	CADHERIN-23 (Mus musculus)	5 / 12	SER A 27 LEU A 66 VAL A 64 PHE A 55 ILE A 97	None	1.28A	1uobA-3mvsA: undetectable	1uobA-3mvsA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	3mvs	CADHERIN-23 (Mus musculus)	4 / 6	ILE A 202 THR A 122 PHE A 155 TYR A 178	None	1.21A	3elzB-3mvsA: undetectable	3elzB-3mvsA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_B_CLMB221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3mvs	CADHERIN-23 (Mus musculus)	5 / 12	THR A 23 LEU A 17 VAL A 95 PHE A 82 PHE A 78	None	1.29A	3u9fB-3mvsA: undetectable 3u9fC-3mvsA: undetectable	3u9fB-3mvsA: 21.65 3u9fC-3mvsA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_L_CLML221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3mvs	CADHERIN-23 (Mus musculus)	5 / 12	PHE A 78 THR A 23 LEU A 17 VAL A 95 PHE A 82	None	1.35A	3u9fJ-3mvsA: undetectable 3u9fL-3mvsA: undetectable	3u9fJ-3mvsA: 21.65 3u9fL-3mvsA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_N_CLMN221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3mvs	CADHERIN-23 (Mus musculus)	5 / 11	THR A 23 LEU A 17 VAL A 95 PHE A 82 PHE A 78	None	1.33A	3u9fN-3mvsA: undetectable 3u9fO-3mvsA: undetectable	3u9fN-3mvsA: 21.65 3u9fO-3mvsA: 21.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UOB_A_PNNA1311_0","DEACETOXYCEPHALOSPORIN C SYNTHETASE","3mvs","CADHERIN-23","Mus musculus",5,"SER A  27;LEU A  66;VAL A  64;PHE A  55;ILE A  97","None","1.28A","1uobA-3mvsA:undetectable","1uobA-3mvsA:21.85"],["3ELZ_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","3mvs","CADHERIN-23","Mus musculus",4,"ILE A 202;THR A 122;PHE A 155;TYR A 178","None","1.21A","3elzB-3mvsA:undetectable","3elzB-3mvsA:21.40"],["3U9F_B_CLMB221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3mvs","CADHERIN-23","Mus musculus",5,"THR A  23;LEU A  17;VAL A  95;PHE A  82;PHE A  78","None","1.29A","3u9fB-3mvsA:undetectable;3u9fC-3mvsA:undetectable","3u9fB-3mvsA:21.65;3u9fC-3mvsA:21.65"],["3U9F_L_CLML221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3mvs","CADHERIN-23","Mus musculus",5,"PHE A  78;THR A  23;LEU A  17;VAL A  95;PHE A  82","None","1.35A","3u9fJ-3mvsA:undetectable;3u9fL-3mvsA:undetectable","3u9fJ-3mvsA:21.65;3u9fL-3mvsA:21.65"],["3U9F_N_CLMN221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","3mvs","CADHERIN-23","Mus musculus",5,"THR A  23;LEU A  17;VAL A  95;PHE A  82;PHE A  78","None","1.33A","3u9fN-3mvsA:undetectable;3u9fO-3mvsA:undetectable","3u9fN-3mvsA:21.65;3u9fO-3mvsA:21.65"]]