SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 PHE A  56
LEU A 134
VAL A 179
VAL A  80
None
1.17A 1dz4A-3mvuA:
undetectable
1dz4A-3mvuA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 8 TYR A  45
PHE A 218
MET A 221
THR A 108
None
IMD  A 226 (-3.6A)
None
None
1.28A 1ea1A-3mvuA:
undetectable
1ea1A-3mvuA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 THR A 212
LEU A 214
GLY A 217
TYR A 117
None
EDO  A 230 ( 4.4A)
None
None
0.90A 1gtiB-3mvuA:
undetectable
1gtiB-3mvuA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 THR A 212
LEU A 214
GLY A 217
TYR A 117
None
EDO  A 230 ( 4.4A)
None
None
0.90A 1gtiE-3mvuA:
undetectable
1gtiE-3mvuA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 THR A 212
LEU A 214
GLY A 217
TYR A 117
None
EDO  A 230 ( 4.4A)
None
None
1.07A 1gtiF-3mvuA:
undetectable
1gtiF-3mvuA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 8 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.90A 1v54C-3mvuA:
undetectable
1v54J-3mvuA:
undetectable
1v54C-3mvuA:
20.30
1v54J-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 1v55C-3mvuA:
1.6
1v55J-3mvuA:
undetectable
1v55C-3mvuA:
20.30
1v55J-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.99A 1v55P-3mvuA:
undetectable
1v55W-3mvuA:
undetectable
1v55P-3mvuA:
20.30
1v55W-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 8 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.90A 2dyrC-3mvuA:
undetectable
2dyrJ-3mvuA:
undetectable
2dyrC-3mvuA:
20.30
2dyrJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.91A 2dysC-3mvuA:
2.5
2dysJ-3mvuA:
undetectable
2dysC-3mvuA:
20.30
2dysJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.96A 2eijC-3mvuA:
1.6
2eijJ-3mvuA:
undetectable
2eijC-3mvuA:
20.30
2eijJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.93A 2eikC-3mvuA:
undetectable
2eikJ-3mvuA:
undetectable
2eikC-3mvuA:
20.30
2eikJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 8 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.91A 2eilC-3mvuA:
undetectable
2eilJ-3mvuA:
undetectable
2eilC-3mvuA:
20.30
2eilJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 2eimC-3mvuA:
3.0
2eimJ-3mvuA:
undetectable
2eimC-3mvuA:
20.30
2eimJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
1.01A 2einC-3mvuA:
2.9
2einJ-3mvuA:
undetectable
2einC-3mvuA:
20.30
2einJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 12 LEU A 122
ARG A 119
PHE A  56
GLY A 128
LEU A 130
None
None
None
EDO  A 235 ( 4.0A)
None
1.30A 2lbdA-3mvuA:
2.4
2lbdA-3mvuA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.90A 2zxwC-3mvuA:
undetectable
2zxwJ-3mvuA:
undetectable
2zxwC-3mvuA:
20.30
2zxwJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.96A 2zxwP-3mvuA:
undetectable
2zxwW-3mvuA:
undetectable
2zxwP-3mvuA:
20.30
2zxwW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.97A 3abkP-3mvuA:
undetectable
3abkW-3mvuA:
undetectable
3abkP-3mvuA:
20.30
3abkW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 3ag1C-3mvuA:
3.1
3ag1J-3mvuA:
undetectable
3ag1C-3mvuA:
20.30
3ag1J-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 3ag4P-3mvuA:
undetectable
3ag4W-3mvuA:
undetectable
3ag4P-3mvuA:
20.30
3ag4W-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 12 TYR A 172
ILE A 147
PHE A 218
GLU A 215
TYR A  45
EDO  A 237 (-4.7A)
None
IMD  A 226 (-3.6A)
IMD  A 226 (-2.8A)
None
1.28A 3apwA-3mvuA:
undetectable
3apwA-3mvuA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.92A 3asnC-3mvuA:
undetectable
3asnJ-3mvuA:
undetectable
3asnC-3mvuA:
20.30
3asnJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
1.00A 3asnP-3mvuA:
3.0
3asnW-3mvuA:
undetectable
3asnP-3mvuA:
20.30
3asnW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
1.00A 3asoP-3mvuA:
undetectable
3asoW-3mvuA:
undetectable
3asoP-3mvuA:
20.30
3asoW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 ILE A 147
THR A 212
PHE A 208
PHE A   9
None
1.17A 3elzB-3mvuA:
undetectable
3elzB-3mvuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 HIS A  25
ARG A 150
GLU A 146
GLN A 173
None
1.25A 3gclA-3mvuA:
undetectable
3gclA-3mvuA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
3 / 3 HIS A  25
ARG A 150
GLU A 146
None
1.05A 3qf1A-3mvuA:
1.4
3qf1A-3mvuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 LEU A  43
LEU A  46
LEU A 105
SER A 101
None
0.94A 3vhuA-3mvuA:
2.3
3vhuA-3mvuA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.98A 3wg7C-3mvuA:
undetectable
3wg7J-3mvuA:
undetectable
3wg7C-3mvuA:
20.30
3wg7J-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 3x2qC-3mvuA:
undetectable
3x2qJ-3mvuA:
undetectable
3x2qC-3mvuA:
20.30
3x2qJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 12 LEU A  62
VAL A 121
GLY A 125
ALA A 124
SER A 127
None
None
None
EDO  A 235 (-4.3A)
None
1.09A 4rrxA-3mvuA:
0.5
4rrxA-3mvuA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 12 LEU A  62
VAL A 121
GLY A 125
ALA A 124
SER A 127
None
None
None
EDO  A 235 (-4.3A)
None
1.09A 4rrxB-3mvuA:
undetectable
4rrxB-3mvuA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 TYR A 172
GLY A 143
TYR A   5
GLY A 180
EDO  A 237 (-4.7A)
None
None
None
1.00A 5ayfA-3mvuA:
undetectable
5ayfA-3mvuA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 5b1aC-3mvuA:
undetectable
5b1aJ-3mvuA:
undetectable
5b1aC-3mvuA:
20.30
5b1aJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 5b1aP-3mvuA:
undetectable
5b1aW-3mvuA:
undetectable
5b1aP-3mvuA:
20.30
5b1aW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.94A 5b1bP-3mvuA:
undetectable
5b1bW-3mvuA:
undetectable
5b1bP-3mvuA:
20.30
5b1bW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A  62
GLY A 125
ALA A 124
SER A 127
None
None
EDO  A 235 (-4.3A)
None
0.81A 5f1aB-3mvuA:
undetectable
5f1aB-3mvuA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 8 LEU A  83
LEU A 137
THR A 118
GLN A  48
None
None
None
CL  A 239 (-4.0A)
1.10A 5hbsA-3mvuA:
undetectable
5hbsA-3mvuA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 12 LEU A  62
VAL A 121
GLY A 125
ALA A 124
SER A 127
None
None
None
EDO  A 235 (-4.3A)
None
1.02A 5ikqA-3mvuA:
undetectable
5ikqA-3mvuA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.96A 5iy5C-3mvuA:
undetectable
5iy5J-3mvuA:
undetectable
5iy5C-3mvuA:
20.60
5iy5J-3mvuA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
1.00A 5iy5P-3mvuA:
undetectable
5iy5W-3mvuA:
undetectable
5iy5P-3mvuA:
20.60
5iy5W-3mvuA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 12 ALA A 112
ILE A 164
GLY A  35
HIS A  44
THR A 224
EDO  A 236 (-3.2A)
None
None
CL  A 239 (-4.0A)
None
1.35A 5jlcA-3mvuA:
undetectable
5jlcA-3mvuA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 6 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.91A 5w97C-3mvuA:
3.1
5w97J-3mvuA:
undetectable
5w97C-3mvuA:
20.30
5w97J-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.98A 5x1fC-3mvuA:
3.1
5x1fJ-3mvuA:
undetectable
5x1fC-3mvuA:
20.30
5x1fJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 7 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.84A 5x1fP-3mvuA:
undetectable
5x1fW-3mvuA:
undetectable
5x1fP-3mvuA:
20.30
5x1fW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.96A 5xdxC-3mvuA:
undetectable
5xdxJ-3mvuA:
undetectable
5xdxC-3mvuA:
20.37
5xdxJ-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
4 / 5 LEU A 204
PHE A 208
LEU A 187
PHE A 195
None
None
None
EDO  A 231 (-3.8A)
0.99A 5xdxP-3mvuA:
undetectable
5xdxW-3mvuA:
undetectable
5xdxP-3mvuA:
20.37
5xdxW-3mvuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)
3mvu TENA FAMILY
TRANSCRIPTIONAL
REGULATOR

(Ruegeria
sp.
TM1040)
5 / 9 VAL A 141
LEU A 133
ALA A  63
VAL A  64
SER A  67
EDO  A 237 ( 4.2A)
None
None
None
None
1.33A 6c2mB-3mvuA:
undetectable
6c2mB-3mvuA:
16.37