SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		5 / 11 ILE A 168
GLY A 171
HIS A 174
LEU A 126
GLY A 256
 None
 1.39A 1i7qA-3mw2A:
undetectable		 1i7qA-3mw2A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		5 / 9 VAL A 268
LEU A 258
ILE A 279
PHE A 254
GLY A  94
 None
 0.91A 4kukA-3mw2A:
undetectable		 4kukA-3mw2A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		5 / 12 GLY A 116
ILE A 245
VAL A 150
VAL A 268
ILE A 243
 None
 0.88A 4q5mA-3mw2A:
undetectable		 4q5mA-3mw2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		5 / 9 ILE A  96
PHE A  89
GLY A  94
ILE A 281
ALA A 280
 None
 1.36A 4yp2B-3mw2A:
undetectable		 4yp2B-3mw2A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		5 / 9 ILE A  96
PHE A  89
GLY A  94
ILE A 281
ALA A 280
 None
 1.37A 5cf9B-3mw2A:
undetectable		 5cf9B-3mw2A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		4 / 7 ILE A 168
HIS A 142
LEU A 126
ALA A 124
 None
 0.90A 5hrqE-3mw2A:
undetectable
5hrqF-3mw2A:
undetectable
5hrqJ-3mw2A:
undetectable		 5hrqE-3mw2A:
6.60
5hrqF-3mw2A:
10.00
5hrqJ-3mw2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		4 / 5 ILE A 244
LEU A 113
HIS A 142
VAL A 125
 None
 1.02A 5jmnB-3mw2A:
undetectable		 5jmnB-3mw2A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3mw2 NEUREXIN-1-ALPHA
(Mus
musculus) 		4 / 6 PHE A 237
ARG A 180
ASN A 264
ASP A 111
 None
 1.26A 6dhbA-3mw2A:
undetectable		 6dhbA-3mw2A:
20.29