SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mw3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 4 GLN A 123
GLN A 257
GLY A  95
HIS A 286
 None
 1.45A 3huoA-3mw3A:
undetectable		 3huoA-3mw3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 7 ARG A 288
ILE A  98
PHE A  91
LEU A 271
 None
 1.10A 4mmcA-3mw3A:
undetectable		 4mmcA-3mw3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		5 / 12 GLY A 118
ILE A 247
VAL A 152
VAL A 270
ILE A 245
 None
 1.00A 4q5mA-3mw3A:
undetectable		 4q5mA-3mw3A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		5 / 11 ILE A 247
TRP A 102
LEU A 268
LEU A 271
ALA A 272
 None
 1.07A 5ji0A-3mw3A:
undetectable		 5ji0A-3mw3A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 4 SER A 125
ALA A 126
GLN A 257
THR A 121
 None
 1.41A 5n0sA-3mw3A:
undetectable		 5n0sA-3mw3A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 4 SER A 125
ALA A 126
GLN A 257
THR A 121
 None
 1.43A 5n0wA-3mw3A:
undetectable		 5n0wA-3mw3A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 4 SER A 125
ALA A 126
GLN A 257
THR A 121
 None
 1.47A 5n0xA-3mw3A:
undetectable		 5n0xA-3mw3A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 8 TRP A 102
THR A 101
TYR A 100
ARG A 130
 None
 1.05A 5tzoA-3mw3A:
undetectable		 5tzoA-3mw3A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 8 LEU A 141
VAL A 152
VAL A 117
VAL A 178
 None
 1.10A 6cp4A-3mw3A:
undetectable		 6cp4A-3mw3A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3mw3 NEUREXIN-2-BETA
(Rattus
norvegicus) 		4 / 6 PHE A 239
ARG A 182
ASN A 266
ASP A 113
 None
 1.28A 6dhbA-3mw3A:
undetectable		 6dhbA-3mw3A:
20.38