SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mw4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		3 / 3 ASP A 109
ARG A 178
ILE A 152
 None
 0.73A 1a4gB-3mw4A:
undetectable		 1a4gB-3mw4A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 6 THR A 207
ASP A 135
ASN A 151
ASP A 156
 None
CA  A   1 (-2.9A)
None
None
 1.06A 2okcA-3mw4A:
undetectable		 2okcA-3mw4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		5 / 12 ALA A 130
PRO A 131
THR A 106
ILE A 127
PHE A 205
 None
 1.11A 2v95A-3mw4A:
undetectable		 2v95A-3mw4A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 8 ILE A 123
GLY A 215
LEU A  93
LEU A  95
 None
 0.88A 2vctB-3mw4A:
undetectable		 2vctB-3mw4A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 4 PRO A 104
THR A 207
GLY A 153
THR A 154
 None
None
CA  A   1 ( 4.2A)
None
 1.06A 3ib1A-3mw4A:
undetectable		 3ib1A-3mw4A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		3 / 3 ASP A 217
ARG A 126
ALA A 212
 None
 0.79A 3mbgC-3mw4A:
undetectable		 3mbgC-3mw4A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 8 VAL A 187
TRP A 190
ASN A 167
HIS A 172
 None
 0.84A 4exsB-3mw4A:
undetectable		 4exsB-3mw4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		6 / 9 LEU A  95
VAL A 236
LEU A 226
ILE A 247
PHE A 222
GLY A  92
 None
 1.16A 4kukA-3mw4A:
undetectable		 4kukA-3mw4A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		5 / 12 GLY A 114
ILE A 213
VAL A 148
VAL A 236
ILE A 211
 None
 1.00A 4q5mA-3mw4A:
undetectable		 4q5mA-3mw4A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 8 VAL A 187
TRP A 190
ASN A 167
HIS A 172
 None
 0.81A 5a5zA-3mw4A:
undetectable		 5a5zA-3mw4A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 7 LEU A 226
GLN A 225
PHE A 222
LEU A 124
 None
 0.89A 5b1aP-3mw4A:
undetectable
5b1aW-3mw4A:
undetectable		 5b1aP-3mw4A:
20.97
5b1aW-3mw4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 7 LEU A 226
GLN A 225
PHE A 222
LEU A 124
 None
 0.91A 5b3sC-3mw4A:
undetectable
5b3sJ-3mw4A:
undetectable		 5b3sC-3mw4A:
20.97
5b3sJ-3mw4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 5 PHE A  87
ILE A 249
GLY A 214
LEU A  93
 None
 0.80A 5dzkB-3mw4A:
undetectable
5dzkI-3mw4A:
undetectable
5dzkW-3mw4A:
undetectable		 5dzkB-3mw4A:
20.52
5dzkI-3mw4A:
23.08
5dzkW-3mw4A:
0.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 5 PHE A  87
ILE A 249
GLY A 214
LEU A  93
 None
 0.78A 5dzkd-3mw4A:
undetectable
5dzkk-3mw4A:
undetectable
5dzky-3mw4A:
undetectable		 5dzkd-3mw4A:
20.52
5dzkk-3mw4A:
23.08
5dzky-3mw4A:
0.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 8 TRP A  98
THR A  97
TYR A  96
ARG A 126
 None
 1.08A 5tzoA-3mw4A:
undetectable		 5tzoA-3mw4A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3mw4 NEUREXIN-2-BETA
(Mus
musculus) 		4 / 8 LEU A 137
VAL A 148
VAL A 113
VAL A 174
 None
 1.06A 6cp4A-3mw4A:
undetectable		 6cp4A-3mw4A:
17.55