SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mw6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PEO_F_CU9F301_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3mw6	UNCHARACTERIZED PROTEIN NMB1681 (Neisseria meningitidis)	4 / 6	THR A 17 GLN A 16 ILE A 27 SER A 13	None	1.23A	3peoG-3mw6A: undetectable	3peoG-3mw6A: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_D_MTXD2000_2 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	3mw6	UNCHARACTERIZED PROTEIN NMB1681 (Neisseria meningitidis)	3 / 3	LEU A 52 ARG A 87 ASN A 92	None	0.69A	3qxvD-3mw6A: undetectable	3qxvD-3mw6A: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3mw6	UNCHARACTERIZED PROTEIN NMB1681 (Neisseria meningitidis)	3 / 3	ARG A 87 PHE A 41 LEU A 81	None	0.91A	5x1bC-3mw6A: undetectable	5x1bC-3mw6A: 19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	3mw6	UNCHARACTERIZED PROTEIN NMB1681 (Neisseria meningitidis)	4 / 7	LEU A 116 ALA A 82 GLN A 103 GLN A 122	None	1.28A	6b89A-3mw6A: undetectable	6b89A-3mw6A: 22.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3PEO_F_CU9F301_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","3mw6","UNCHARACTERIZED PROTEIN NMB1681","Neisseria meningitidis",4,"THR A  17;GLN A  16;ILE A  27;SER A  13","None","1.23A","3peoG-3mw6A:undetectable","3peoG-3mw6A:19.56"],["3QXV_D_MTXD2000_2","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","3mw6","UNCHARACTERIZED PROTEIN NMB1681","Neisseria meningitidis",3,"LEU A  52;ARG A  87;ASN A  92","None","0.69A","3qxvD-3mw6A:undetectable","3qxvD-3mw6A:19.33"],["5X1B_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3","3mw6","UNCHARACTERIZED PROTEIN NMB1681","Neisseria meningitidis",3,"ARG A  87;PHE A  41;LEU A  81","None","0.91A","5x1bC-3mw6A:undetectable","5x1bC-3mw6A:19.16"],["6B89_B_NOVB403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","3mw6","UNCHARACTERIZED PROTEIN NMB1681","Neisseria meningitidis",4,"LEU A 116;ALA A  82;GLN A 103;GLN A 122","None","1.28A","6b89A-3mw6A:undetectable","6b89A-3mw6A:22.94"]]