SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mwb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		3 / 3 ASP A  69
PHE A 243
ARG A 233
 None
 0.89A 2a3aA-3mwbA:
undetectable		 2a3aA-3mwbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		5 / 10 PHE A 220
PHE A 273
ALA A 252
VAL A 257
TYR A 277
 None
 1.30A 2d06B-3mwbA:
0.0		 2d06B-3mwbA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		4 / 7 ALA A  66
THR A  67
ALA A  70
PRO A  55
 None
 0.98A 2ql8A-3mwbA:
undetectable
2ql8B-3mwbA:
undetectable		 2ql8A-3mwbA:
19.37
2ql8B-3mwbA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		4 / 4 SER A 132
SER A 106
THR A 107
SER A 137
 None
 1.35A 3loqA-3mwbA:
undetectable		 3loqA-3mwbA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		4 / 7 LEU A  99
ALA A 150
VAL A 129
ILE A 102
 None
 0.95A 3wsjB-3mwbA:
undetectable		 3wsjB-3mwbA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		4 / 6 THR A  14
GLU A  61
THR A  16
THR A  39
 None
 0.98A 4pgfA-3mwbA:
undetectable		 4pgfA-3mwbA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		3 / 3 PRO A 191
LEU A 183
SER A 276
 None
 0.82A 5fsaB-3mwbA:
undetectable		 5fsaB-3mwbA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		4 / 7 HIS A 110
ASP A  69
THR A  65
HIS A 108
 None
 1.37A 5iy5A-3mwbA:
undetectable
5iy5C-3mwbA:
undetectable		 5iy5A-3mwbA:
20.97
5iy5C-3mwbA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3mwb PREPHENATE
DEHYDRATASE
(Paenarthrobacter
aurescens) 		4 / 4 LEU A 141
GLY A 140
SER A 137
SER A 106
 None
 1.31A 5uunB-3mwbA:
undetectable		 5uunB-3mwbA:
23.80