SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 3mwj HEAT RESISTANT RNA
DEPENDENT ATPASE
(Thermus
thermophilus) 		4 / 7 LEU A  78
ALA A 148
SER A 182
THR A 178
 None
 0.87A 1dvxA-3mwjA:
undetectable		 1dvxA-3mwjA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3mwj HEAT RESISTANT RNA
DEPENDENT ATPASE
(Thermus
thermophilus) 		3 / 3 THR A  79
VAL A  77
GLU A 152
 None
 0.61A 3v4tA-3mwjA:
0.9
3v4tD-3mwjA:
0.9		 3v4tA-3mwjA:
21.09
3v4tD-3mwjA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3mwj HEAT RESISTANT RNA
DEPENDENT ATPASE
(Thermus
thermophilus) 		3 / 3 GLY A  48
GLN A  87
LYS A  51
 None
 0.74A 5imsB-3mwjA:
3.2		 5imsB-3mwjA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3mwj HEAT RESISTANT RNA
DEPENDENT ATPASE
(Thermus
thermophilus) 		5 / 12 VAL A 125
THR A  79
LEU A  99
PHE A  55
VAL A 147
 None
 1.17A 6a93B-3mwjA:
undetectable		 6a93B-3mwjA:
20.63