SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		6 / 12 PHE A  29
LEU A  67
ILE A 126
ALA A  96
VAL A  99
LEU A  23
 None
 1.27A 1cbsA-3mwmA:
undetectable		 1cbsA-3mwmA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		5 / 12 PHE A  29
LEU A  67
ILE A 126
ALA A  96
VAL A  99
 None
 0.98A 2fr3A-3mwmA:
undetectable		 2fr3A-3mwmA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 HIS A  84
HIS A  86
HIS A 122
 ZN  A 142 (-3.1A)
ZN  A 142 (-3.2A)
ZN  A 142 (-3.2A)
 0.61A 3qpkA-3mwmA:
undetectable		 3qpkA-3mwmA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 HIS A 122
HIS A  86
HIS A  84
 ZN  A 142 (-3.2A)
ZN  A 142 (-3.2A)
ZN  A 142 (-3.1A)
 0.50A 3qpkA-3mwmA:
undetectable		 3qpkA-3mwmA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 HIS A  84
HIS A  86
HIS A 122
 ZN  A 142 (-3.1A)
ZN  A 142 (-3.2A)
ZN  A 142 (-3.2A)
 0.59A 3qpkB-3mwmA:
undetectable		 3qpkB-3mwmA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 HIS A 122
HIS A  86
HIS A  84
 ZN  A 142 (-3.2A)
ZN  A 142 (-3.2A)
ZN  A 142 (-3.1A)
 0.48A 3qpkB-3mwmA:
undetectable		 3qpkB-3mwmA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		4 / 6 LEU A  67
CYH A  90
CYH A  93
HIS A  87
 None
ZN  A 140 (-2.3A)
ZN  A 140 (-2.2A)
ZN  A 141 (-3.1A)
 1.29A 5hrqD-3mwmA:
undetectable
5hrqG-3mwmA:
undetectable
5hrqH-3mwmA:
undetectable		 5hrqD-3mwmA:
15.38
5hrqG-3mwmA:
8.70
5hrqH-3mwmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 HIS A  84
HIS A  86
HIS A 122
 ZN  A 142 (-3.1A)
ZN  A 142 (-3.2A)
ZN  A 142 (-3.2A)
 0.55A 5migA-3mwmA:
undetectable		 5migA-3mwmA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3mwm PUTATIVE METAL
UPTAKE REGULATION
PROTEIN
(Streptomyces
coelicolor) 		3 / 3 HIS A 122
HIS A  86
HIS A  84
 ZN  A 142 (-3.2A)
ZN  A 142 (-3.2A)
ZN  A 142 (-3.1A)
 0.45A 5migA-3mwmA:
undetectable		 5migA-3mwmA:
14.39