SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mwn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3mwn PHYCOERYTHRIN
(Phormidium
tenue) 		5 / 10 THR A1134
LEU A1159
LEU A1156
VAL A1052
VAL A1051
 None
None
None
None
CYC  A3002 ( 4.5A)
 1.25A 3lxiA-3mwnA:
undetectable		 3lxiA-3mwnA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3mwn PHYCOERYTHRIN
(Phormidium
tenue) 		5 / 9 THR A1134
LEU A1159
LEU A1156
VAL A1052
VAL A1051
 None
None
None
None
CYC  A3002 ( 4.5A)
 1.26A 4c9kB-3mwnA:
undetectable		 4c9kB-3mwnA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3mwn PHYCOERYTHRIN
(Phormidium
tenue) 		5 / 9 THR A1134
LEU A1159
LEU A1156
VAL A1052
VAL A1051
 None
None
None
None
CYC  A3002 ( 4.5A)
 1.26A 4c9pA-3mwnA:
undetectable		 4c9pA-3mwnA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3mwn PHYCOERYTHRIN
(Phormidium
tenue) 		3 / 3 ASP A1057
ASN A1080
GLN A1076
 None
 0.79A 5k7uA-3mwnA:
undetectable		 5k7uA-3mwnA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3mwn PHYCOERYTHRIN
(Phormidium
tenue) 		4 / 8 LEU A1138
MET A1144
LEU A1044
ILE A1093
 CYC  A3002 (-4.0A)
None
CYC  A3002 (-3.9A)
None
 0.98A 5mzjA-3mwnA:
undetectable		 5mzjA-3mwnA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3mwn PHYCOERYTHRIN
(Phormidium
tenue) 		4 / 5 VAL A1051
LEU A1156
CYH A1153
ASP A1143
 CYC  A3002 ( 4.5A)
None
None
CYC  A3002 ( 3.8A)
 1.29A 5vcvA-3mwnA:
undetectable		 5vcvA-3mwnA:
21.32