SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 6 VAL A 194
VAL A 189
ILE A 145
ARG A  82
 None
 1.10A 1iepA-3mx0A:
undetectable		 1iepA-3mx0A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 11 ASN A  84
VAL A  86
ILE A  96
THR A  83
LEU A 180
 None
 1.19A 3bf1A-3mx0A:
undetectable
3bf1B-3mx0A:
undetectable		 3bf1A-3mx0A:
20.19
3bf1B-3mx0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 11 ASN A  84
VAL A  86
ILE A  96
THR A  83
LEU A 180
 None
 1.20A 3bf1E-3mx0A:
undetectable
3bf1F-3mx0A:
undetectable		 3bf1E-3mx0A:
20.19
3bf1F-3mx0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		5 / 11 THR A  83
LEU A 180
ASN A  84
VAL A  86
ILE A  96
 None
 1.21A 3bf1E-3mx0A:
undetectable
3bf1F-3mx0A:
undetectable		 3bf1E-3mx0A:
20.19
3bf1F-3mx0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 7 VAL A 194
VAL A 189
ILE A 145
ARG A  82
 None
 1.07A 3mssB-3mx0A:
undetectable		 3mssB-3mx0A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 TYR A 334
THR A 336
THR A 349
 None
 0.70A 5aoxB-3mx0A:
undetectable		 5aoxB-3mx0A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3mx0 EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		3 / 3 TYR A 334
THR A 336
THR A 349
 None
 0.73A 5aoxE-3mx0A:
undetectable		 5aoxE-3mx0A:
11.78