SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mx9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 112
LEU A 106
VAL A 105
ILE A  23
LEU A  78
 None
 1.18A 1s19A-3mx9A:
undetectable		 1s19A-3mx9A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 303
LEU A 297
VAL A 296
ILE A 214
LEU A 269
 None
 1.17A 1s19A-3mx9A:
undetectable		 1s19A-3mx9A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 204
PHE A 278
GLY A 256
TYR A 267
PHE A 200
 None
 1.15A 1zz1B-3mx9A:
undetectable
1zz1C-3mx9A:
undetectable		 1zz1B-3mx9A:
20.73
1zz1C-3mx9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A  91
LEU A  88
LEU A  78
LEU A  58
 None
 0.85A 2ab2A-3mx9A:
undetectable		 2ab2A-3mx9A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A 282
LEU A 279
LEU A 269
LEU A 249
 None
 0.74A 2ab2A-3mx9A:
undetectable		 2ab2A-3mx9A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  91
LEU A  88
PHE A  87
LEU A  84
VAL A  45
 None
 1.10A 2pnjA-3mx9A:
undetectable		 2pnjA-3mx9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 8 LEU A  58
ARG A  51
LEU A 288
GLY A  19
 None
None
None
CA  A 364 (-4.1A)
 1.01A 2po5A-3mx9A:
undetectable		 2po5A-3mx9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 7 TYR A   5
LEU A 106
PHE A  43
VAL A  45
 None
 1.16A 3jwqC-3mx9A:
undetectable		 3jwqC-3mx9A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 4 PHE A  43
TYR A   5
ILE A 108
LEU A 104
 None
 1.46A 3sudA-3mx9A:
undetectable		 3sudA-3mx9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 7 ARG A  68
ARG A  40
ILE A  24
TYR A  44
 None
 1.34A 5a06B-3mx9A:
undetectable		 5a06B-3mx9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_1
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 7 SER A 118
LYS A  34
PHE A  35
HIS A  37
 None
 1.49A 5dlvB-3mx9A:
1.6		 5dlvB-3mx9A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLW_A_5D5A905_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  84
PHE A   9
PHE A  43
VAL A  64
TYR A  76
 None
 1.36A 5dlwA-3mx9A:
0.0		 5dlwA-3mx9A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mx9 PROTEIN SCV3V2(G19S)
(Chlamydomonas
reinhardtii) 		4 / 4 GLN A 283
THR A 280
GLU A 301
LEU A 232
 None
 1.37A 5m66A-3mx9A:
undetectable		 5m66A-3mx9A:
20.77