SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3mxq SENSOR PROTEIN
(Vibrio
cholerae) 		5 / 12 SER A  37
LEU A  87
PHE A  55
VAL A  39
VAL A  22
 None
 1.22A 1q23H-3mxqA:
undetectable
1q23I-3mxqA:
undetectable		 1q23H-3mxqA:
20.18
1q23I-3mxqA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 3mxq SENSOR PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A  86
PHE A  55
LEU A  62
VAL A 121
VAL A  31
 None
 1.17A 2hrcB-3mxqA:
undetectable		 2hrcB-3mxqA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mxq SENSOR PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A  86
PHE A  55
LEU A  62
VAL A 121
VAL A  31
 None
 1.22A 2po5A-3mxqA:
undetectable		 2po5A-3mxqA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mxq SENSOR PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU A  86
PHE A  55
LEU A  62
VAL A 121
VAL A  31
 None
 1.19A 2po5B-3mxqA:
undetectable		 2po5B-3mxqA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3mxq SENSOR PROTEIN
(Vibrio
cholerae) 		5 / 11 ILE A  51
ILE A  28
GLY A  48
PHE A  35
GLY A  43
 None
 1.05A 4ac9B-3mxqA:
undetectable
4ac9C-3mxqA:
undetectable		 4ac9B-3mxqA:
16.60
4ac9C-3mxqA:
16.60