SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z2B_C_VLBC800_2 (TUBULIN ALPHA CHAIN)	3mxu	GLYCINE CLEAVAGE SYSTEM H PROTEIN (Bartonella henselae)	4 / 5	PRO A 84 VAL A 87 ASN A 88 VAL A 56	None	0.94A	1z2bC-3mxuA: undetectable	1z2bC-3mxuA: 16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWV_A_RFXA801_1 (TRANSPORTER)	3mxu	GLYCINE CLEAVAGE SYSTEM H PROTEIN (Bartonella henselae)	5 / 12	LEU A 32 GLY A 33 LEU A 35 ILE A 24 ASP A 26	None	1.00A	3gwvA-3mxuA: undetectable	3gwvA-3mxuA: 13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A9K_B_TYLB2198_1 (CREB-BINDING PROTEIN)	3mxu	GLYCINE CLEAVAGE SYSTEM H PROTEIN (Bartonella henselae)	4 / 5	VAL A 87 LEU A 35 ILE A 38 VAL A 65	None	0.98A	4a9kB-3mxuA: undetectable	4a9kB-3mxuA: 25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B8I_C_FK5C201_2 (CALCINEURIN SUBUNIT B, VARIANT PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	3mxu	GLYCINE CLEAVAGE SYSTEM H PROTEIN (Bartonella henselae)	4 / 4	LEU A 47 MET A 100 VAL A 73 ASN A 43	None	1.15A	5b8iB-3mxuA: undetectable	5b8iB-3mxuA: 21.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Z2B_C_VLBC800_2","TUBULIN ALPHA CHAIN","3mxu","GLYCINE CLEAVAGE SYSTEM H PROTEIN","Bartonella henselae",4,"PRO A  84;VAL A  87;ASN A  88;VAL A  56","None","0.94A","1z2bC-3mxuA:undetectable","1z2bC-3mxuA:16.14"],["3GWV_A_RFXA801_1","TRANSPORTER","3mxu","GLYCINE CLEAVAGE SYSTEM H PROTEIN","Bartonella henselae",5,"LEU A  32;GLY A  33;LEU A  35;ILE A  24;ASP A  26","None","1.00A","3gwvA-3mxuA:undetectable","3gwvA-3mxuA:13.51"],["4A9K_B_TYLB2198_1","CREB-BINDING PROTEIN","3mxu","GLYCINE CLEAVAGE SYSTEM H PROTEIN","Bartonella henselae",4,"VAL A  87;LEU A  35;ILE A  38;VAL A  65","None","0.98A","4a9kB-3mxuA:undetectable","4a9kB-3mxuA:25.49"],["5B8I_C_FK5C201_2","CALCINEURIN SUBUNIT B, VARIANT;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","3mxu","GLYCINE CLEAVAGE SYSTEM H PROTEIN","Bartonella henselae",4,"LEU A  47;MET A 100;VAL A  73;ASN A  43","None","1.15A","5b8iB-3mxuA:undetectable","5b8iB-3mxuA:21.11"]]