SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3my0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 ( 3.8A)
None
 0.98A 1iepB-3my0A:
24.9		 1iepB-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
GLU A 242
LEU A 275
THR A 277
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.81A 1m17A-3my0A:
26.4		 1m17A-3my0A:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 9 GLY A 209
VAL A 216
ALA A 227
LEU A 257
TYR A 279
LEU A 337
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-4.6A)
 0.97A 1muoA-3my0A:
16.3		 1muoA-3my0A:
28.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 6 GLY A 309
VAL A 336
ALA A 306
SER A 305
 None
 1.03A 1p6kA-3my0A:
undetectable		 1p6kA-3my0A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 ALA A 227
LEU A 257
THR A 277
LEU A 313
HIS A 328
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
None
None
 0.50A 1uwhA-3my0A:
24.9		 1uwhA-3my0A:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
LYS A 229
LEU A 257
THR A 277
LEU A 313
HIS A 328
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
None
None
 0.63A 1uwhB-3my0A:
24.9		 1uwhB-3my0A:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
LEU A 257
THR A 277
LEU A 313
HIS A 328
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
None
None
 0.53A 1uwjA-3my0A:
9.5		 1uwjA-3my0A:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
LEU A 257
THR A 277
LEU A 313
HIS A 328
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
None
None
 0.53A 1uwjB-3my0A:
9.6		 1uwjB-3my0A:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 11 VAL A 208
GLY A 209
VAL A 216
ALA A 227
TYR A 279
SER A 284
LEU A 337
 LDN  A 600 ( 4.4A)
None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.7A)
None
LDN  A 600 (-4.6A)
 0.81A 2evaA-3my0A:
26.1		 2evaA-3my0A:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
GLU A 242
THR A 277
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.66A 2gqgA-3my0A:
27.1		 2gqgA-3my0A:
28.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.74A 2hyyA-3my0A:
25.0		 2hyyA-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.71A 2hyyA-3my0A:
25.0		 2hyyA-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.74A 2hyyB-3my0A:
25.2		 2hyyB-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.78A 2hyyB-3my0A:
25.2		 2hyyB-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
GLY A 283
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 ( 3.8A)
None
 1.37A 2hyyC-3my0A:
25.2		 2hyyC-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
THR A 277
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.85A 2hyyC-3my0A:
25.2		 2hyyC-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 ( 3.8A)
None
 0.94A 2hyyD-3my0A:
24.9		 2hyyD-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.76A 2hyyD-3my0A:
24.9		 2hyyD-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
GLY A 283
ASP A 287
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-3.8A)
LDN  A 600 (-4.6A)
 1.05A 2itzA-3my0A:
26.1		 2itzA-3my0A:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.72A 2oiqA-3my0A:
24.8		 2oiqA-3my0A:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 6 LEU A 251
TYR A 246
ILE A 326
ILE A 256
 None
 0.97A 2q8hA-3my0A:
undetectable		 2q8hA-3my0A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 GLY A 209
VAL A 216
ALA A 227
LEU A 257
TYR A 279
GLY A 283
ALA A 347
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 ( 3.8A)
 0.78A 2wgjA-3my0A:
24.5		 2wgjA-3my0A:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LEU A 257
TYR A 279
GLY A 283
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 ( 3.8A)
None
 0.85A 2wgjA-3my0A:
24.5		 2wgjA-3my0A:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.47A 2y6oA-3my0A:
25.4		 2y6oA-3my0A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 7 MET A 354
ASP A 363
VAL A 249
ILE A 245
 None
 1.05A 2yfbA-3my0A:
undetectable		 2yfbA-3my0A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
HIS A 328
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.40A 3cs9A-3my0A:
25.0		 3cs9A-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 ALA A 227
THR A 277
GLY A 283
HIS A 328
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
None
LDN  A 600 ( 3.8A)
 0.40A 3cs9B-3my0A:
25.0		 3cs9B-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
ILE A 245
THR A 277
HIS A 328
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
None
LDN  A 600 ( 3.8A)
None
 0.95A 3cs9C-3my0A:
25.0		 3cs9C-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 ALA A 227
THR A 277
GLY A 283
HIS A 328
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
None
LDN  A 600 ( 3.8A)
 0.35A 3cs9D-3my0A:
23.8		 3cs9D-3my0A:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.60A 3g5dA-3my0A:
26.4		 3g5dA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.59A 3g5dA-3my0A:
26.4		 3g5dA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		9 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.71A 3g5dB-3my0A:
26.5		 3g5dB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.95A 3gvuA-3my0A:
25.3		 3gvuA-3my0A:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 208
VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
 LDN  A 600 ( 4.4A)
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.93A 3hegA-3my0A:
16.1		 3hegA-3my0A:
26.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.67A 3k54A-3my0A:
25.6		 3k54A-3my0A:
27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.76A 3k5vA-3my0A:
17.2		 3k5vA-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.77A 3k5vA-3my0A:
17.2		 3k5vA-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.75A 3k5vB-3my0A:
24.2		 3k5vB-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.77A 3k5vB-3my0A:
24.2		 3k5vB-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 ( 3.8A)
None
 0.94A 3ms9A-3my0A:
24.8		 3ms9A-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.73A 3ms9A-3my0A:
24.8		 3ms9A-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 ( 3.8A)
None
 0.97A 3mssA-3my0A:
24.9		 3mssA-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.75A 3mssA-3my0A:
24.9		 3mssA-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 ( 3.8A)
None
 0.97A 3mssC-3my0A:
25.0		 3mssC-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.77A 3mssC-3my0A:
25.0		 3mssC-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.72A 3mssD-3my0A:
24.9		 3mssD-3my0A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.59A 3octA-3my0A:
25.4		 3octA-3my0A:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.39A 3oezA-3my0A:
24.7		 3oezA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-4.6A)
 0.79A 3oezB-3my0A:
24.8		 3oezB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
TYR A 279
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.64A 3oezB-3my0A:
24.8		 3oezB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.34A 3og7A-3my0A:
25.0		 3og7A-3my0A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 208
GLY A 209
VAL A 216
ALA A 227
LYS A 229
THR A 277
LEU A 337
 LDN  A 600 ( 4.4A)
None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
 0.88A 3ohtA-3my0A:
15.5		 3ohtA-3my0A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_1
(P38A)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 GLY A 209
VAL A 216
ALA A 227
LYS A 229
THR A 277
LEU A 337
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
 0.88A 3ohtB-3my0A:
4.5		 3ohtB-3my0A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
THR A 277
GLY A 283
HIS A 328
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
None
LDN  A 600 ( 3.8A)
None
 0.74A 3oxzA-3my0A:
24.9		 3oxzA-3my0A:
28.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.69A 3pyyB-3my0A:
24.7		 3pyyB-3my0A:
28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.65A 3qlgA-3my0A:
25.6		 3qlgA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.73A 3qlgB-3my0A:
26.5		 3qlgB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 ALA A 227
LYS A 229
THR A 277
LEU A 313
HIS A 328
ARG A 329
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
None
None
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.95A 3zosA-3my0A:
23.7		 3zosA-3my0A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 ALA A 227
LYS A 229
THR A 277
LEU A 313
HIS A 328
ARG A 329
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
None
None
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.98A 3zosB-3my0A:
23.9		 3zosB-3my0A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
THR A 277
LEU A 313
HIS A 328
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.86A 3zosB-3my0A:
23.9		 3zosB-3my0A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
ILE A 245
THR A 277
TYR A 279
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.85A 4bkjA-3my0A:
23.9		 4bkjA-3my0A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 1.25A 4bkjA-3my0A:
23.9		 4bkjA-3my0A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 1.22A 4bkjB-3my0A:
24.1		 4bkjB-3my0A:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LEU A 257
THR A 277
HIS A 328
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.66A 4c8bA-3my0A:
23.9		 4c8bA-3my0A:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
LEU A 257
THR A 277
HIS A 328
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.55A 4c8bA-3my0A:
23.9		 4c8bA-3my0A:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 5 VAL A 216
ILE A 256
TYR A 279
ILE A 346
 LDN  A 600 (-4.5A)
None
LDN  A 600 (-4.7A)
None
 0.76A 4c8bA-3my0A:
23.9		 4c8bA-3my0A:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 ALA A 227
LYS A 229
ILE A 256
LEU A 257
THR A 277
HIS A 328
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
None
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.73A 4c8bB-3my0A:
24.0		 4c8bB-3my0A:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ILE A 256
LEU A 257
THR A 277
HIS A 328
LEU A 337
ALA A 347
ASP A 348
 None
None
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.81A 4c8bB-3my0A:
24.0		 4c8bB-3my0A:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKI_A_ADNA2022_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 11 GLY A 209
VAL A 216
ALA A 227
TYR A 279
GLY A 283
SER A 284
LEU A 337
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
None
LDN  A 600 (-4.6A)
 0.81A 4ckiA-3my0A:
27.4		 4ckiA-3my0A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
GLU A 242
ILE A 245
THR A 277
TYR A 279
LEU A 337
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-4.6A)
None
 1.18A 4csvA-3my0A:
25.9		 4csvA-3my0A:
27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
ILE A 245
THR A 277
TYR A 279
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 1.10A 4csvA-3my0A:
25.9		 4csvA-3my0A:
27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXO_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.76A 4mxoB-3my0A:
26.5		 4mxoB-3my0A:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXX_A_DB8A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.57A 4mxxA-3my0A:
26.3		 4mxxA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXX_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.56A 4mxxB-3my0A:
25.0		 4mxxB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
GLU A 242
TYR A 279
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.77A 4mxyB-3my0A:
26.8		 4mxyB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
TYR A 279
GLY A 283
LEU A 337
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
None
 0.87A 4mxyB-3my0A:
26.8		 4mxyB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
GLU A 242
TYR A 279
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.77A 4mxzB-3my0A:
26.8		 4mxzB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
TYR A 279
GLY A 283
LEU A 337
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
None
 0.87A 4mxzB-3my0A:
26.8		 4mxzB-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0S_A_ADNA500_1
(AURORA KINASE A)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 11 GLY A 209
VAL A 216
ALA A 227
LYS A 229
LEU A 257
ASN A 335
LEU A 337
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.5A)
LDN  A 600 (-4.6A)
 0.85A 4o0sA-3my0A:
24.1		 4o0sA-3my0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 6 VAL A 216
ALA A 227
LEU A 257
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.6A)
 0.49A 4o0uA-3my0A:
8.8		 4o0uA-3my0A:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 LYS A 229
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.73A 4otwA-3my0A:
24.6		 4otwA-3my0A:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
LYS A 229
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.68A 4otwA-3my0A:
24.6		 4otwA-3my0A:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
LEU A 337
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.6A)
None
 1.11A 4r7iA-3my0A:
24.9		 4r7iA-3my0A:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 ALA A 227
LYS A 229
LEU A 257
THR A 277
SER A 284
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
None
 0.76A 4rzvA-3my0A:
9.8		 4rzvA-3my0A:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
SER A 284
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
None
 0.74A 4rzvB-3my0A:
25.1		 4rzvB-3my0A:
27.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_2
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
THR A 277
GLY A 283
HIS A 328
LEU A 337
ASP A 348
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
None
LDN  A 600 (-4.6A)
None
 0.85A 4u0iA-3my0A:
24.8		 4u0iA-3my0A:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 11 VAL A 216
ALA A 227
TYR A 279
GLY A 283
ASN A 335
LEU A 337
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.5A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.72A 4u5jA-3my0A:
27.6		 4u5jA-3my0A:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 ALA A 227
LEU A 313
HIS A 328
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
None
None
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.55A 4uxqA-3my0A:
25.3		 4uxqA-3my0A:
29.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 9 VAL A 216
LYS A 229
TYR A 279
ARG A 329
LEU A 337
ILE A 346
 LDN  A 600 (-4.5A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
None
LDN  A 600 (-4.6A)
None
 1.04A 4v01B-3my0A:
24.5		 4v01B-3my0A:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
HIS A 328
ALA A 347
ASP A 348
GLY A 350
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 ( 3.8A)
None
None
 0.93A 4v04A-3my0A:
24.1		 4v04A-3my0A:
30.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
LEU A 313
HIS A 328
ALA A 347
ASP A 348
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
None
LDN  A 600 ( 3.8A)
None
 1.12A 4v04A-3my0A:
24.1		 4v04A-3my0A:
30.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 11 ALA A 227
THR A 277
GLY A 283
ASN A 335
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.5A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.48A 4wa9A-3my0A:
24.1		 4wa9A-3my0A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
THR A 277
GLY A 283
ASN A 335
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.5A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.80A 4wa9B-3my0A:
25.6		 4wa9B-3my0A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.63A 4xeyA-3my0A:
26.3		 4xeyA-3my0A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.61A 4xeyB-3my0A:
26.1		 4xeyB-3my0A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.64A 4xliA-3my0A:
27.2		 4xliA-3my0A:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.63A 4xliA-3my0A:
27.2		 4xliA-3my0A:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.59A 4xliB-3my0A:
27.1		 4xliB-3my0A:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		3 / 3 ASP A 235
LEU A 351
GLY A 350
 None
 0.37A 4xmfA-3my0A:
undetectable		 4xmfA-3my0A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.44A 4xv2A-3my0A:
24.4		 4xv2A-3my0A:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 GLY A 209
ALA A 227
GLY A 283
LEU A 337
ALA A 347
ASP A 348
 None
LDN  A 600 (-3.2A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
None
 0.76A 5ajqA-3my0A:
16.6		 5ajqA-3my0A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.75A 5bvwA-3my0A:
24.3		 5bvwA-3my0A:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.45A 5cswA-3my0A:
24.4		 5cswA-3my0A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 PHE A 231
VAL A 216
ALA A 227
LEU A 257
THR A 277
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
 0.86A 5cswB-3my0A:
24.2		 5cswB-3my0A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.54A 5cswB-3my0A:
24.2		 5cswB-3my0A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
LEU A 257
THR A 277
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.74A 5h2uA-3my0A:
25.4		 5h2uA-3my0A:
29.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 VAL A 216
ALA A 227
LEU A 257
THR A 277
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.75A 5h2uB-3my0A:
25.7		 5h2uB-3my0A:
29.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
TYR A 279
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
 0.36A 5hesB-3my0A:
24.5		 5hesB-3my0A:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
LYS A 229
LEU A 257
THR A 277
LEU A 313
HIS A 328
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
None
None
 0.72A 5hi2A-3my0A:
24.9		 5hi2A-3my0A:
28.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 PHE A 231
VAL A 216
ALA A 227
LEU A 257
THR A 277
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
 0.78A 5hieA-3my0A:
24.7		 5hieA-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.40A 5hieA-3my0A:
24.7		 5hieA-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 PHE A 231
VAL A 216
ALA A 227
LEU A 257
THR A 277
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
 0.80A 5hieB-3my0A:
24.5		 5hieB-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.40A 5hieB-3my0A:
24.5		 5hieB-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 GLY A 209
GLY A 214
PHE A 231
VAL A 216
ALA A 227
THR A 277
 None
None
None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
 1.42A 5hieC-3my0A:
25.0		 5hieC-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 GLY A 209
PHE A 231
VAL A 216
ALA A 227
LEU A 257
THR A 277
 None
None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
 0.80A 5hieC-3my0A:
25.0		 5hieC-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 GLY A 209
VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.52A 5hieC-3my0A:
25.0		 5hieC-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 PHE A 231
VAL A 216
ALA A 227
LEU A 257
THR A 277
 None
LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
 0.79A 5hieD-3my0A:
24.6		 5hieD-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		5 / 12 VAL A 216
ALA A 227
LYS A 229
LEU A 257
THR A 277
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
 0.38A 5hieD-3my0A:
24.6		 5hieD-3my0A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		6 / 12 ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.51A 5i9xA-3my0A:
25.5		 5i9xA-3my0A:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 ALA A 227
LYS A 229
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.70A 5i9yA-3my0A:
25.4		 5i9yA-3my0A:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 7 GLY A 209
GLY A 211
GLY A 214
VAL A 216
 None
None
None
LDN  A 600 (-4.5A)
 0.33A 5izjB-3my0A:
21.1		 5izjB-3my0A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 7 GLY A 209
GLY A 211
VAL A 216
LYS A 229
 None
None
LDN  A 600 (-4.5A)
LDN  A 600 (-4.0A)
 0.35A 5izjA-3my0A:
21.4		 5izjA-3my0A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 7 GLY A 209
GLY A 211
VAL A 216
LYS A 229
 None
None
LDN  A 600 (-4.5A)
LDN  A 600 (-4.0A)
 0.25A 5j5xA-3my0A:
22.1		 5j5xA-3my0A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		8 / 12 GLU A 206
GLY A 209
ALA A 227
GLU A 242
TYR A 279
GLY A 283
ASP A 287
ASP A 348
 None
None
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-3.8A)
None
 0.75A 5vc3A-3my0A:
25.1		 5vc3A-3my0A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.67A 6bsdA-3my0A:
23.9		 6bsdA-3my0A:
11.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		7 / 12 VAL A 216
ALA A 227
LYS A 229
GLU A 242
THR A 277
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.80A 6fnmA-3my0A:
25.7		 6fnmA-3my0A:
30.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3
(Homo
sapiens) 		4 / 7 ILE A 276
GLU A 224
HIS A 222
VAL A 202
 None
 1.07A 6j20A-3my0A:
1.5		 6j20A-3my0A:
19.26