SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3my9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 8 ALA A  53
LEU A  39
LEU A 126
LEU A 112
 None
 0.72A 1dvtA-3my9A:
undetectable
1dvtB-3my9A:
undetectable		 1dvtA-3my9A:
16.62
1dvtB-3my9A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 6 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.08A 1iepA-3my9A:
undetectable		 1iepA-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		5 / 11 LEU A 357
GLY A 358
ILE A 359
SER A 360
ILE A 361
 None
 0.52A 2kawA-3my9A:
undetectable		 2kawA-3my9A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 7 GLY A 205
ALA A 206
MET A 207
LEU A 210
 None
 0.64A 2wekB-3my9A:
undetectable		 2wekB-3my9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		3 / 3 SER A 140
ASP A 149
ASP A 196
 None
None
MG  A 378 ( 4.2A)
 0.61A 3iv6A-3my9A:
undetectable		 3iv6A-3my9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		3 / 3 SER A 140
ASP A 149
ASP A 196
 None
None
MG  A 378 ( 4.2A)
 0.61A 3iv6C-3my9A:
undetectable		 3iv6C-3my9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 6 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.05A 3k5vB-3my9A:
undetectable		 3k5vB-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 6 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.04A 3ms9A-3my9A:
undetectable		 3ms9A-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 7 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.07A 3ms9B-3my9A:
undetectable		 3ms9B-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 6 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.07A 3mssA-3my9A:
undetectable		 3mssA-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 7 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.07A 3mssB-3my9A:
undetectable		 3mssB-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 6 VAL A   6
VAL A  86
ILE A 114
MET A 279
 None
 1.06A 3mssC-3my9A:
undetectable		 3mssC-3my9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		5 / 12 ILE A 221
THR A 242
ALA A 215
LEU A 195
LEU A 180
 None
 1.25A 4pbhA-3my9A:
undetectable		 4pbhA-3my9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		5 / 12 ILE A 272
GLY A 297
PRO A 352
VAL A 351
ILE A 135
 None
 0.98A 4q5mA-3my9A:
undetectable		 4q5mA-3my9A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		5 / 12 ILE A 209
HIS A 173
GLY A 169
PHE A 236
PHE A 216
 None
 1.20A 5ih0A-3my9A:
undetectable		 5ih0A-3my9A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		5 / 12 ILE A 209
HIS A 173
PHE A 236
PHE A 216
MET A 166
 None
 1.36A 5iwuA-3my9A:
undetectable		 5iwuA-3my9A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 4 GLU A 222
PRO A 224
ILE A 221
LEU A 245
 MG  A 378 (-3.1A)
None
None
None
 1.29A 5m45D-3my9A:
1.2		 5m45D-3my9A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 4 GLU A 222
PRO A 224
ILE A 221
LEU A 245
 MG  A 378 (-3.1A)
None
None
None
 1.31A 5m45G-3my9A:
undetectable		 5m45G-3my9A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 4 GLU A 222
PRO A 224
ILE A 221
LEU A 245
 MG  A 378 (-3.1A)
None
None
None
 1.30A 5m45J-3my9A:
undetectable		 5m45J-3my9A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		6 / 12 ALA A 237
VAL A 260
GLY A 292
ALA A 291
LEU A 284
LEU A 256
 MG  A 377 (-4.2A)
None
None
None
None
None
 1.46A 5xxiA-3my9A:
undetectable		 5xxiA-3my9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		5 / 10 SER A 122
GLY A 356
ILE A 342
ALA A 308
PHE A 220
 None
 0.97A 5zjiA-3my9A:
undetectable
5zjiJ-3my9A:
undetectable		 5zjiA-3my9A:
11.33
5zjiJ-3my9A:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		4 / 6 SER A 138
TYR A 296
ASP A 196
GLU A 222
 None
None
MG  A 378 ( 4.2A)
MG  A 378 (-3.1A)
 1.33A 6djzA-3my9A:
undetectable		 6djzA-3my9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3my9 MUCONATE
CYCLOISOMERASE
(Azorhizobium
caulinodans) 		3 / 3 TRP A   3
ILE A 114
GLU A   8
 None
 0.78A 6hcxA-3my9A:
undetectable		 6hcxA-3my9A:
11.54