SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3myb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 178
LEU A 162
ALA A 118
ALA A 109
GLY A 135
 None
None
None
None
GOL  A 300 (-4.1A)
 0.95A 3c6gA-3mybA:
undetectable		 3c6gA-3mybA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ALA A 109
PHE A  62
LEU A 178
ALA A 103
 None
 0.95A 3hrdA-3mybA:
undetectable
3hrdB-3mybA:
undetectable		 3hrdA-3mybA:
22.76
3hrdB-3mybA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		6 / 12 VAL A 117
ALA A 132
PHE A 131
LEU A 176
LEU A 178
LEU A 162
 None
 1.47A 4i1rA-3mybA:
undetectable		 4i1rA-3mybA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 THR A 126
ASN A  27
PHE A  26
 None
 0.74A 4pd9A-3mybA:
undetectable		 4pd9A-3mybA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A  31
LEU A  68
LEU A   5
GLY A  65
ALA A 111
 None
None
None
None
GOL  A 300 (-3.6A)
 1.30A 4retC-3mybA:
undetectable		 4retC-3mybA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A  64
GLY A  65
ALA A 111
THR A 110
CYH A 142
 None
None
GOL  A 300 (-3.6A)
GOL  A 300 ( 4.7A)
None
 1.33A 5l5zH-3mybA:
undetectable
5l5zI-3mybA:
undetectable		 5l5zH-3mybA:
23.84
5l5zI-3mybA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A  64
GLY A  65
ALA A 111
THR A 110
CYH A 142
 None
None
GOL  A 300 (-3.6A)
GOL  A 300 ( 4.7A)
None
 1.33A 5l5zV-3mybA:
undetectable
5l5zW-3mybA:
undetectable		 5l5zV-3mybA:
23.84
5l5zW-3mybA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3myb ENOYL-COA HYDRATASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 165
VAL A 168
VAL A 153
ALA A 157
LEU A 149
 None
 1.07A 6czmA-3mybA:
undetectable
6czmC-3mybA:
undetectable		 6czmA-3mybA:
23.58
6czmC-3mybA:
23.58