SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3myd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APX_A_Z80A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	5 / 12	VAL A 573 PHE A 624 GLU A 580 LEU A 712 ARG A 695	None	1.48A	3apxA-3mydA: undetectable	3apxA-3mydA: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_A_ADNA300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	5 / 11	ALA A 569 VAL A 573 ILE A 565 THR A 595 ALA A 598	None	0.79A	3kw2A-3mydA: undetectable	3kw2A-3mydA: 24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_B_ADNB300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	5 / 11	ALA A 569 VAL A 573 ILE A 565 THR A 595 ALA A 598	None	0.76A	3kw2B-3mydA: undetectable	3kw2B-3mydA: 24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OGP_A_017A200_2 (FIV PROTEASE)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	5 / 10	LEU A 634 VAL A 711 ILE A 668 VAL A 686 LEU A 688	None	0.91A	3ogpB-3mydA: undetectable	3ogpB-3mydA: 14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TYE_B_YTZB902_1 (DIHYDROPTEROATE SYNTHASE)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	3 / 3	PHE A 723 LYS A 625 SER A 626	None	1.16A	3tyeB-3mydA: undetectable	3tyeB-3mydA: 24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_C_SVRC516_1 (RNA-DEPENDENT RNA POLYMERASE)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	5 / 9	PRO A 566 GLY A 568 ALA A 569 ASP A 604 LEU A 608	None	1.16A	3ur0C-3mydA: undetectable	3ur0C-3mydA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DO3_B_0LAB602_1 (FATTY-ACID AMIDE HYDROLASE 1)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	4 / 6	LEU A 644 LEU A 667 ILE A 668 MET A 702	None	1.00A	4do3B-3mydA: undetectable	4do3B-3mydA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEA_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	3myd	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA (Helicobacter pylori)	4 / 5	LEU A 657 LYS A 647 LEU A 659 GLU A 663	None	1.26A	5weaA-3mydA: undetectable	5weaA-3mydA: 17.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3APX_A_Z80A190_1","ALPHA-1-ACID GLYCOPROTEIN 2","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",5,"VAL A 573;PHE A 624;GLU A 580;LEU A 712;ARG A 695","None","1.48A","3apxA-3mydA:undetectable","3apxA-3mydA:17.82"],["3KW2_A_ADNA300_1","PROBABLE R-RNA METHYLTRANSFERASE","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",5,"ALA A 569;VAL A 573;ILE A 565;THR A 595;ALA A 598","None","0.79A","3kw2A-3mydA:undetectable","3kw2A-3mydA:24.52"],["3KW2_B_ADNB300_1","PROBABLE R-RNA METHYLTRANSFERASE","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",5,"ALA A 569;VAL A 573;ILE A 565;THR A 595;ALA A 598","None","0.76A","3kw2B-3mydA:undetectable","3kw2B-3mydA:24.52"],["3OGP_A_017A200_2","FIV PROTEASE;FIV PROTEASE","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",5,"LEU A 634;VAL A 711;ILE A 668;VAL A 686;LEU A 688","None","0.91A","3ogpB-3mydA:undetectable","3ogpB-3mydA:14.24"],["3TYE_B_YTZB902_1","DIHYDROPTEROATE SYNTHASE","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",3,"PHE A 723;LYS A 625;SER A 626","None","1.16A","3tyeB-3mydA:undetectable","3tyeB-3mydA:24.80"],["3UR0_C_SVRC516_1","RNA-DEPENDENT RNA POLYMERASE","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",5,"PRO A 566;GLY A 568;ALA A 569;ASP A 604;LEU A 608","None","1.16A","3ur0C-3mydA:undetectable","3ur0C-3mydA:22.41"],["4DO3_B_0LAB602_1","FATTY-ACID AMIDE HYDROLASE 1","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",4,"LEU A 644;LEU A 667;ILE A 668;MET A 702","None","1.00A","4do3B-3mydA:undetectable","4do3B-3mydA:21.47"],["5WEA_A_IPHA901_0","PROTEIN ARGONAUTE-2","3myd","FLAGELLAR BIOSYNTHESIS PROTEIN FLHA","Helicobacter pylori",4,"LEU A 657;LYS A 647;LEU A 659;GLU A 663","None","1.26A","5weaA-3mydA:undetectable","5weaA-3mydA:17.81"]]