SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3myo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 ILE A  20
ALA A  22
ALA A  63
THR A  84
LEU A 299
 None
 1.03A 1cbsA-3myoA:
undetectable		 1cbsA-3myoA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 GLY A 303
LEU A  59
LEU A  23
LEU A 310
ALA A 253
 None
 0.92A 1gseB-3myoA:
undetectable		 1gseB-3myoA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 8 SER A  21
ILE A  19
GLY A  18
GLY A  85
 None
 0.78A 1me7A-3myoA:
4.9		 1me7A-3myoA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 9 TYR A 144
ILE A 145
TYR A  90
ILE A 148
GLU A 151
 None
 1.33A 1mrgA-3myoA:
undetectable		 1mrgA-3myoA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 8 TYR A 144
ILE A 145
TYR A  90
ILE A 148
GLU A 151
 None
 1.22A 1mrjA-3myoA:
undetectable		 1mrjA-3myoA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 8 ARG A  80
SER A  64
VAL A  14
TRP A 321
 None
 1.36A 1u1jA-3myoA:
6.4		 1u1jA-3myoA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 5 PRO A 208
VAL A 186
ASN A 187
VAL A 205
 None
 1.03A 1z2bC-3myoA:
undetectable		 1z2bC-3myoA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 ILE A  20
ALA A  22
ALA A  63
THR A  84
LEU A 299
 None
 1.06A 2fr3A-3myoA:
undetectable		 2fr3A-3myoA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 8 LEU A  59
LEU A  23
LEU A 310
ALA A 253
 None
 0.77A 2vcvP-3myoA:
undetectable		 2vcvP-3myoA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 SER A 248
ILE A 307
LEU A 310
LEU A 314
VAL A 273
 None
 1.18A 3dcjA-3myoA:
undetectable
3dcjB-3myoA:
undetectable		 3dcjA-3myoA:
24.27
3dcjB-3myoA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		3 / 3 VAL A  55
LYS A  52
HIS A  38
 None
 0.92A 3elzA-3myoA:
undetectable		 3elzA-3myoA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 5 LEU A  67
ILE A  20
ALA A 122
PHE A 160
 None
 0.78A 4dc3B-3myoA:
undetectable		 4dc3B-3myoA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EBK_A_TOYA301_1
(AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 9 GLU A 292
GLU A  49
ASP A  69
GLU A  57
ALA A  76
 None
 1.50A 4ebkA-3myoA:
0.0
4ebkB-3myoA:
0.0		 4ebkA-3myoA:
24.64
4ebkB-3myoA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 7 GLY A  94
ALA A  89
GLU A  91
GLN A  33
 None
 0.92A 4g0uB-3myoA:
undetectable		 4g0uB-3myoA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 6 GLY A  94
ALA A  89
GLU A  91
GLN A  33
 None
 0.93A 4g0uA-3myoA:
undetectable		 4g0uA-3myoA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		3 / 3 ARG A  28
GLU A 109
TYR A  72
 None
 0.77A 4r29D-3myoA:
undetectable		 4r29D-3myoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 9 TYR A 144
ILE A 145
TYR A  90
ILE A 148
GLU A 151
 None
 1.09A 4yp2B-3myoA:
undetectable		 4yp2B-3myoA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 9 TYR A 144
ILE A 145
TYR A  90
ILE A 148
GLU A 151
 None
 1.09A 5cf9B-3myoA:
undetectable		 5cf9B-3myoA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		3 / 3 SER A  15
SER A  64
PHE A 160
 None
 0.89A 5mugA-3myoA:
undetectable		 5mugA-3myoA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 7 PRO A 104
TYR A 144
ILE A 148
ILE A 145
 None
 0.88A 5murB-3myoA:
undetectable		 5murB-3myoA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 ILE A 307
LEU A  59
TRP A 298
SER A 248
GLY A 276
 None
 1.21A 5nnaA-3myoA:
undetectable		 5nnaA-3myoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 ILE A 307
LEU A  59
TRP A 298
SER A 248
GLY A 276
 None
 1.20A 5nnaB-3myoA:
undetectable		 5nnaB-3myoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 ILE A 307
LEU A  59
TRP A 298
SER A 248
GLY A 276
 None
 1.19A 5nnaC-3myoA:
undetectable		 5nnaC-3myoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 ILE A 307
LEU A  59
TRP A 298
SER A 248
GLY A 276
 None
 1.22A 5nnaD-3myoA:
undetectable		 5nnaD-3myoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 LEU A 255
VAL A 251
PHE A 262
PHE A 233
ALA A 232
 None
 0.81A 5uxdB-3myoA:
undetectable		 5uxdB-3myoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		4 / 6 TYR A 144
TYR A  90
ILE A 148
GLU A 151
 None
 1.02A 5z3jA-3myoA:
undetectable		 5z3jA-3myoA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1
(Streptococcus
pyogenes) 		5 / 12 GLY A  29
SER A 283
LEU A  54
VAL A  55
ASP A  69
 None
 1.16A 6bxmA-3myoA:
undetectable		 6bxmA-3myoA:
21.35