SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3myu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		3 / 3 PHE A  51
TYR A 348
TYR A 345
 None
 0.56A 1x70B-3myuA:
undetectable		 1x70B-3myuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		3 / 3 PHE A  91
TYR A 348
TYR A 345
 None
 0.79A 1x70B-3myuA:
undetectable		 1x70B-3myuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 5 TYR A 176
SER A 216
SER A 218
ASN A  95
 VIB  A 500 (-3.8A)
None
None
VIB  A 500 ( 4.8A)
 1.07A 1yvpA-3myuA:
undetectable		 1yvpA-3myuA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		3 / 3 PHE A 328
PHE A  55
PHE A  52
 None
 0.49A 2od9A-3myuA:
undetectable		 2od9A-3myuA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		3 / 3 PHE A 328
PHE A  55
PHE A  52
 None
 0.49A 2qqgA-3myuA:
undetectable		 2qqgA-3myuA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		5 / 12 ILE A  67
ASN A  37
LEU A  59
ILE A 324
ALA A 323
 None
 1.02A 3a50A-3myuA:
undetectable		 3a50A-3myuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		5 / 12 ILE A  67
ASN A  72
LEU A  59
ILE A 324
ALA A 323
 None
 1.09A 3a50A-3myuA:
undetectable		 3a50A-3myuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.09A 3fwgA-3myuA:
undetectable		 3fwgA-3myuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		3 / 3 ASP A 268
SER A 272
ARG A 255
 None
 0.98A 3loqA-3myuA:
undetectable		 3loqA-3myuA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.13A 3wrhE-3myuA:
undetectable		 3wrhE-3myuA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.11A 3wrjE-3myuA:
undetectable		 3wrjE-3myuA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 5 PHE A  36
PHE A  55
ILE A 324
GLY A 325
 None
 0.79A 4ejjC-3myuA:
undetectable		 4ejjC-3myuA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.12A 4ek1A-3myuA:
undetectable		 4ek1A-3myuA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.14A 4g3rA-3myuA:
undetectable		 4g3rA-3myuA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		5 / 12 LEU A 331
ASP A 337
PHE A  93
LEU A  34
PHE A  91
 None
 1.13A 4iaqA-3myuA:
undetectable		 4iaqA-3myuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		5 / 12 LEU A 331
ASP A 337
PHE A  93
LEU A  34
PHE A  91
 None
 1.21A 4iarA-3myuA:
undetectable		 4iarA-3myuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.13A 4kkyX-3myuA:
undetectable		 4kkyX-3myuA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 6 PHE A  36
LEU A  59
VAL A 312
ASP A  90
 None
 1.11A 4l4cA-3myuA:
undetectable		 4l4cA-3myuA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 7 LEU A  59
ALA A 323
LEU A  63
LEU A  34
 None
 0.65A 4z90F-3myuA:
undetectable
4z90G-3myuA:
undetectable
4z90H-3myuA:
undetectable
4z90J-3myuA:
undetectable		 4z90F-3myuA:
21.43
4z90G-3myuA:
21.43
4z90H-3myuA:
21.43
4z90J-3myuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		4 / 4 TYR A 320
GLY A  61
SER A  60
LEU A  59
 None
 1.39A 5bphC-3myuA:
undetectable		 5bphC-3myuA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3myu HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37
(Mycoplasma
genitalium) 		5 / 12 ILE A 343
GLY A 344
ILE A 111
PHE A 328
TYR A 348
 VIB  A 500 (-4.8A)
VIB  A 500 (-3.6A)
None
None
None
 1.22A 5igwA-3myuA:
undetectable		 5igwA-3myuA:
23.99