SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3myv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 SER A 290
GLY A 292
LEU A 341
GLY A  60
PHE A  64
 None
None
EDO  A 505 ( 4.7A)
None
EDO  A 505 (-3.8A)
 0.87A 1fduC-3myvA:
undetectable		 1fduC-3myvA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 SER A 290
GLY A 292
LEU A 341
GLY A  60
PHE A  64
 None
None
EDO  A 505 ( 4.7A)
None
EDO  A 505 (-3.8A)
 0.96A 1iolA-3myvA:
undetectable		 1iolA-3myvA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 TYR A 298
TRP A 297
TYR A 330
GLY A 332
 None
None
EDO  A 503 ( 3.9A)
None
 1.30A 1mxgA-3myvA:
undetectable		 1mxgA-3myvA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A 224
ARG A 152
ILE A 193
 EDO  A 516 (-3.0A)
EDO  A 516 (-3.8A)
None
 0.78A 1uobA-3myvA:
undetectable		 1uobA-3myvA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 417
GLY A  67
ARG A 224
ASP A  68
ALA A  62
 None
None
EDO  A 516 (-3.0A)
None
None
 1.25A 2br4B-3myvA:
undetectable		 2br4B-3myvA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 TYR A 255
ALA A 253
GLU A 388
ILE A 389
TYR A 364
 EDO  A 509 (-4.7A)
None
EDO  A 519 ( 4.9A)
None
None
 1.24A 2dm6A-3myvA:
undetectable
2dm6B-3myvA:
undetectable		 2dm6A-3myvA:
20.86
2dm6B-3myvA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 321
ASP A 316
ARG A 408
ASP A 319
 None
 1.08A 2e5dA-3myvA:
undetectable
2e5dB-3myvA:
undetectable		 2e5dA-3myvA:
21.60
2e5dB-3myvA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASP A 319
ARG A 321
ASP A 316
ARG A 408
 None
 1.08A 2e5dA-3myvA:
undetectable
2e5dB-3myvA:
undetectable		 2e5dA-3myvA:
21.60
2e5dB-3myvA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO6_A_ETVA302_1
(DEOXYCYTIDINE KINASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLU A 362
LEU A 221
ARG A 413
ASP A 426
TYR A  59
 None
None
None
None
EDO  A 516 (-4.8A)
 1.42A 2no6A-3myvA:
undetectable		 2no6A-3myvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 THR A 196
LEU A 109
ALA A 144
LEU A  49
LEU A 197
 None
 1.08A 2npnA-3myvA:
undetectable		 2npnA-3myvA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 MET A  63
ARG A 429
GLY A  71
MET A  74
 None
 1.05A 2pnjB-3myvA:
undetectable		 2pnjB-3myvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 MET A  63
ARG A 429
GLY A  71
MET A  74
 None
 1.23A 3aqiB-3myvA:
undetectable		 3aqiB-3myvA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 GLN A 312
ASP A  72
ASP A  68
THR A 306
 None
 1.39A 3bwcB-3myvA:
undetectable		 3bwcB-3myvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A 224
VAL A 186
THR A 151
 EDO  A 516 (-3.0A)
None
None
 0.87A 3nduD-3myvA:
undetectable		 3nduD-3myvA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 HIS A 422
TYR A  59
LEU A 358
MET A 213
 EDO  A 516 ( 4.3A)
EDO  A 516 (-4.8A)
None
None
 1.38A 3uzzB-3myvA:
undetectable		 3uzzB-3myvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ASP A 316
ASN A 397
GLU A 412
ASP A 396
 None
 1.12A 4gkiC-3myvA:
undetectable		 4gkiC-3myvA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 ARG A 183
GLY A 155
SER A 165
LEU A 166
 None
 1.14A 5bphA-3myvA:
undetectable		 5bphA-3myvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ARG A 183
GLY A 155
SER A 165
LEU A 166
 None
 0.95A 5bphB-3myvA:
undetectable		 5bphB-3myvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 ARG A 183
GLY A 155
SER A 165
LEU A 166
 None
 0.96A 5bphD-3myvA:
undetectable		 5bphD-3myvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A 429
HIS A 422
ARG A 413
 None
EDO  A 516 ( 4.3A)
None
 1.15A 5iaoC-3myvA:
undetectable		 5iaoC-3myvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ARG A 429
HIS A 422
ARG A 413
 None
EDO  A 516 ( 4.3A)
None
 1.13A 5iaoF-3myvA:
undetectable		 5iaoF-3myvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 ILE A 124
LEU A 116
VAL A  46
LEU A  49
GLU A 111
 None
 1.41A 5tixB-3myvA:
undetectable		 5tixB-3myvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASP A  73
ASP A  72
GLN A 312
TYR A 440
 None
 1.40A 6g31G-3myvA:
undetectable		 6g31G-3myvA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3myv SUSD SUPERFAMILY
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 ASP A  51
ILE A 108
PRO A 105
LEU A  52
 None
 1.41A 6mkeA-3myvA:
undetectable		 6mkeA-3myvA:
10.98