SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 ALA A 290
VAL A 285
TRP A 284
 None
 0.81A 1kqeA-3mz1A:
undetectable
1kqeE-3mz1A:
undetectable		 1kqeA-3mz1A:
2.14
1kqeE-3mz1A:
2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 ALA A 290
VAL A 285
TRP A 284
 None
 0.79A 1kqeB-3mz1A:
undetectable
1kqeD-3mz1A:
undetectable		 1kqeB-3mz1A:
2.14
1kqeD-3mz1A:
2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 TRP A 284
ALA A 290
VAL A 285
 None
 0.81A 1kqeB-3mz1A:
undetectable
1kqeD-3mz1A:
undetectable		 1kqeB-3mz1A:
2.14
1kqeD-3mz1A:
2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 TRP A 284
ALA A 290
VAL A 285
 None
 0.81A 1kqeA-3mz1A:
undetectable
1kqeE-3mz1A:
undetectable		 1kqeA-3mz1A:
2.14
1kqeE-3mz1A:
2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		4 / 7 PHE A 239
PRO A 237
ALA A  95
PHE A  96
 None
 1.23A 1lqtA-3mz1A:
undetectable		 1lqtA-3mz1A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_ACTB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		4 / 4 HIS A 169
PRO A 170
ASN A 181
TYR A 183
 None
 1.18A 2f7aB-3mz1A:
12.6		 2f7aB-3mz1A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		4 / 5 ILE A 102
LEU A 105
ALA A  97
PHE A 281
 None
 0.95A 2opxA-3mz1A:
undetectable		 2opxA-3mz1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		4 / 6 LEU A 245
ALA A 236
LEU A 224
ALA A 227
 None
 0.85A 2vcvB-3mz1A:
undetectable		 2vcvB-3mz1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		4 / 6 LEU A 245
ALA A 236
LEU A 224
ALA A 227
 None
 0.96A 2vcvK-3mz1A:
undetectable		 2vcvK-3mz1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 SER A  94
ASP A 123
ASN A 218
 None
 0.82A 3lsfB-3mz1A:
7.9
3lsfE-3mz1A:
8.0		 3lsfB-3mz1A:
21.54
3lsfE-3mz1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 ASP A 123
ASN A 218
SER A  94
 None
 0.82A 3lsfB-3mz1A:
7.9
3lsfE-3mz1A:
7.7		 3lsfB-3mz1A:
21.54
3lsfE-3mz1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		4 / 5 VAL A  90
LEU A 119
ILE A 117
VAL A 285
 None
 0.95A 4a9kB-3mz1A:
undetectable		 4a9kB-3mz1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		5 / 12 THR A 221
THR A 222
ALA A 225
ALA A 226
CYH A 160
 None
 1.42A 4u15A-3mz1A:
undetectable		 4u15A-3mz1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 VAL A 241
GLN A 235
CYH A 160
 None
 0.77A 5icxA-3mz1A:
undetectable
5icxE-3mz1A:
undetectable		 5icxA-3mz1A:
22.26
5icxE-3mz1A:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		3 / 3 VAL A 241
GLN A 235
CYH A 160
 None
 0.85A 5icxC-3mz1A:
undetectable
5icxF-3mz1A:
undetectable		 5icxC-3mz1A:
22.26
5icxF-3mz1A:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3mz1 PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Sinorhizobium
meliloti) 		5 / 12 ILE A 117
LEU A 278
PHE A 281
THR A  92
ILE A 137
 None
 1.26A 5z6fA-3mz1A:
undetectable		 5z6fA-3mz1A:
19.48