SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A  63
ALA A 149
THR A 157
ILE A  90
 None
 0.81A 1utdB-3mz2A:
undetectable
1utdC-3mz2A:
undetectable		 1utdB-3mz2A:
16.07
1utdC-3mz2A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A  63
ALA A 149
THR A 157
ILE A  90
 None
 0.81A 1utdJ-3mz2A:
undetectable
1utdK-3mz2A:
undetectable		 1utdJ-3mz2A:
16.07
1utdK-3mz2A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 5 LYS A 156
SER A  39
LEU A 316
SER A 314
 None
 1.38A 3ijxH-3mz2A:
undetectable		 3ijxH-3mz2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 4 LYS A 156
SER A  39
LEU A 316
SER A 314
 None
 1.37A 3ik6H-3mz2A:
0.0		 3ik6H-3mz2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 5 LYS A 156
SER A  39
LEU A 316
SER A 314
 None
 1.41A 3iluH-3mz2A:
undetectable		 3iluH-3mz2A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 143
ASN A  72
PRO A  70
LEU A 131
 None
 1.20A 3oi8A-3mz2A:
undetectable		 3oi8A-3mz2A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 7 PRO A 225
TYR A 219
ARG A 195
ALA A 194
 None
 1.08A 3twpB-3mz2A:
undetectable		 3twpB-3mz2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 7 PRO A 225
TYR A 219
ARG A 195
ALA A 194
 None
 1.09A 3twpC-3mz2A:
undetectable		 3twpC-3mz2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		4 / 7 ARG A 110
ASN A  72
GLU A  71
ARG A  65
 SO4  A   9 ( 3.9A)
None
SO4  A   9 ( 4.8A)
SO4  A   9 ( 2.9A)
 1.21A 6b8kA-3mz2A:
undetectable		 6b8kA-3mz2A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3mz2 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Parabacteroides
distasonis) 		3 / 3 LYS A 311
SER A 307
SER A 308
 None
 1.04A 6gbfA-3mz2A:
undetectable		 6gbfA-3mz2A:
21.43