SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 3mzh PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
CRP/FNR-FAMILY)
(Mycobacterium
tuberculosis) 		4 / 5 ILE A  83
SER A  82
PRO A  86
PRO A  88
 None
CMP  A 623 (-2.7A)
None
None
 1.42A 3bjwC-3mzhA:
undetectable		 3bjwC-3mzhA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_I_DIFI1006_1
(SERUM ALBUMIN)		 3mzh PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
CRP/FNR-FAMILY)
(Mycobacterium
tuberculosis) 		5 / 10 PHE A  11
ARG A  46
LEU A  47
ILE A  49
SER A 103
 None
 1.00A 4z69I-3mzhA:
undetectable		 4z69I-3mzhA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3mzh PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
CRP/FNR-FAMILY)
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  96
ALA A  93
THR A  94
VAL A  99
 None
 0.91A 5eclD-3mzhA:
undetectable		 5eclD-3mzhA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3mzh PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
CRP/FNR-FAMILY)
(Mycobacterium
tuberculosis) 		4 / 7 VAL A  55
ILE A  57
VAL A  37
ALA A  93
 None
CMP  A 623 ( 4.1A)
None
None
 0.68A 5ospA-3mzhA:
undetectable		 5ospA-3mzhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3mzh PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
CRP/FNR-FAMILY)
(Mycobacterium
tuberculosis) 		4 / 7 VAL A  55
ILE A  57
VAL A  37
ALA A  93
 None
CMP  A 623 ( 4.1A)
None
None
 0.69A 5osrA-3mzhA:
undetectable		 5osrA-3mzhA:
21.78