SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		5 / 12 MET A 189
LEU A 142
ILE A  40
SER A 177
PHE A 181
 None
 1.35A 1xotA-3mzoA:
4.3		 1xotA-3mzoA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		5 / 11 ASP A  68
HIS A  67
ASP A 137
GLU A 144
LEU A 141
 CA  A 301 ( 2.6A)
CA  A 301 ( 4.0A)
CA  A 301 (-2.7A)
None
None
 1.18A 2q0jB-3mzoA:
undetectable		 2q0jB-3mzoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		5 / 11 ASP A  68
HIS A  67
ASP A 137
LEU A 141
HIS A  33
 CA  A 301 ( 2.6A)
CA  A 301 ( 4.0A)
CA  A 301 (-2.7A)
None
CA  A 301 (-3.8A)
 1.28A 2q0jB-3mzoA:
undetectable		 2q0jB-3mzoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		4 / 6 VAL A  37
HIS A  33
SER A  34
THR A  38
 None
CA  A 301 (-3.8A)
None
None
 1.11A 3tj7A-3mzoA:
undetectable
3tj7B-3mzoA:
undetectable		 3tj7A-3mzoA:
21.21
3tj7B-3mzoA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		4 / 6 VAL A  37
HIS A  33
SER A  34
THR A  38
 None
CA  A 301 (-3.8A)
None
None
 1.11A 3tj7C-3mzoA:
undetectable
3tj7D-3mzoA:
undetectable		 3tj7C-3mzoA:
21.21
3tj7D-3mzoA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		4 / 6 VAL A  37
HIS A  33
SER A  34
THR A  38
 None
CA  A 301 (-3.8A)
None
None
 1.10A 3tj7C-3mzoA:
undetectable
3tj7D-3mzoA:
undetectable		 3tj7C-3mzoA:
21.21
3tj7D-3mzoA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		4 / 6 LEU A 119
PRO A 114
GLN A 113
TYR A 116
 None
 1.46A 3vkxA-3mzoA:
undetectable		 3vkxA-3mzoA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		5 / 12 ALA A  41
GLY A 123
GLY A 130
ASP A 125
ALA A  64
 None
None
None
CA  A 307 ( 4.8A)
None
 1.11A 4lg1C-3mzoA:
undetectable		 4lg1C-3mzoA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		5 / 11 ILE A 132
GLY A  45
ALA A  41
LEU A 133
VAL A  37
 None
 1.31A 5hw4B-3mzoA:
undetectable		 5hw4B-3mzoA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		5 / 12 MET A 175
ALA A 176
TYR A 180
PHE A  43
VAL A  55
 None
 1.26A 6hu9N-3mzoA:
undetectable		 6hu9N-3mzoA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3mzo LIN2634 PROTEIN
(Listeria
innocua) 		4 / 6 ILE A  16
ALA A  31
ARG A  18
ASP A 137
 None
None
CA  A 301 (-4.1A)
CA  A 301 (-2.7A)
 1.16A 6hu9m-3mzoA:
undetectable
6hu9q-3mzoA:
undetectable		 6hu9m-3mzoA:
18.78
6hu9q-3mzoA:
17.35