SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3n01 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE-LIKE N
(Homo
sapiens) 		4 / 6 LEU A 483
VAL A 487
LYS A 488
ILE A 507
 None
 0.78A 2piwA-3n01A:
undetectable		 2piwA-3n01A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3n01 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE-LIKE N
(Homo
sapiens) 		5 / 12 GLY A 555
GLY A 553
LEU A 527
ILE A 549
LEU A 514
 None
 1.11A 2zbpA-3n01A:
3.4		 2zbpA-3n01A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3n01 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE-LIKE N
(Homo
sapiens) 		5 / 12 ALA A 534
ILE A 518
ASN A 521
LEU A 525
GLN A 523
 None
 1.16A 4r3aA-3n01A:
undetectable		 4r3aA-3n01A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3n01 RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE-LIKE N
(Homo
sapiens) 		3 / 3 ARG A 519
ILE A 505
SER A 503
 None
 0.63A 5zw2A-3n01A:
undetectable		 5zw2A-3n01A:
11.94