SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 3n07 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 VAL A 166
LEU A 169
ALA A 173
ILE A 120
ILE A  23
 None
 0.89A 1fk6A-3n07A:
undetectable		 1fk6A-3n07A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3n07 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 VAL A 163
VAL A  30
VAL A  80
ARG A  83
GLY A  56
 None
 1.13A 2cbrA-3n07A:
undetectable		 2cbrA-3n07A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)		 3n07 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 7 LYS A  49
ASP A  31
ASP A  29
PHE A  51
 None
None
MG  A 200 (-2.5A)
None
 1.44A 2pk4A-3n07A:
undetectable		 2pk4A-3n07A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3n07 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 6 ARG A  54
GLY A  58
VAL A 163
HIS A  52
 None
 1.05A 4oltA-3n07A:
undetectable		 4oltA-3n07A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3n07 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 6 ARG A  54
GLY A  58
VAL A 163
HIS A  52
 None
 1.05A 4oltB-3n07A:
undetectable		 4oltB-3n07A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3n07 3-DEOXY-D-MANNO-OCTU
LOSONATE 8-PHOSPHATE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 6 VAL A 129
VAL A 133
TYR A 119
ILE A 106
 None
 0.93A 5pbeA-3n07A:
undetectable		 5pbeA-3n07A:
19.43