SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n08'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3n08 PUTATIVE
PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(PEBP)
(Chlamydia
trachomatis) 		4 / 8 SER A  32
SER A  30
ALA A 141
LEU A 143
 None
CL  A 155 (-3.0A)
None
None
 0.98A 4iklA-3n08A:
2.9
4iklB-3n08A:
2.9		 4iklA-3n08A:
21.15
4iklB-3n08A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3n08 PUTATIVE
PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(PEBP)
(Chlamydia
trachomatis) 		5 / 12 LEU A 118
ALA A 132
LEU A 130
THR A 140
ILE A  44
 None
 1.12A 4x1yB-3n08A:
undetectable		 4x1yB-3n08A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3n08 PUTATIVE
PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(PEBP)
(Chlamydia
trachomatis) 		4 / 8 GLY A  58
ARG A 106
VAL A  50
ASP A  49
 None
 0.67A 5vlmA-3n08A:
undetectable		 5vlmA-3n08A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3n08 PUTATIVE
PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
(PEBP)
(Chlamydia
trachomatis) 		4 / 5 ALA A  83
TYR A  66
GLN A  85
ILE A  64
 None
 1.32A 6f6sA-3n08A:
undetectable
6f6sB-3n08A:
undetectable		 6f6sA-3n08A:
23.97
6f6sB-3n08A:
24.03