SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 GLU A 257
ILE A 256
ARG A 249
 None
 0.82A 1cd2A-3n0gA:
undetectable		 1cd2A-3n0gA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 LEU A 275
ILE A 274
PHE A 593
PRO A 592
 None
 0.98A 1oniB-3n0gA:
undetectable
1oniC-3n0gA:
undetectable		 1oniB-3n0gA:
15.84
1oniC-3n0gA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 GLU A 423
ASN A 441
TRP A 426
 DST  A 601 ( 3.3A)
None
None
 1.15A 1r15C-3n0gA:
undetectable		 1r15C-3n0gA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 GLU A 423
ASN A 441
TRP A 426
 DST  A 601 ( 3.3A)
None
None
 1.12A 1r15D-3n0gA:
undetectable		 1r15D-3n0gA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 GLU A 423
ASN A 441
TRP A 426
 DST  A 601 ( 3.3A)
None
None
 1.15A 1r15E-3n0gA:
undetectable		 1r15E-3n0gA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 GLU A 423
ASN A 441
TRP A 426
 DST  A 601 ( 3.3A)
None
None
 1.13A 1r15F-3n0gA:
undetectable		 1r15F-3n0gA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 8 PHE A 435
ASP A 490
THR A 434
TYR A 438
 None
MG  A 622 ( 4.5A)
None
None
 1.12A 1rmtD-3n0gA:
undetectable		 1rmtD-3n0gA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 8 ARG A 249
SER A 282
LEU A 272
LEU A 119
 None
 0.90A 2bfpC-3n0gA:
undetectable		 2bfpC-3n0gA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		5 / 10 SER A 198
ALA A 152
PHE A 155
ALA A 169
LEU A 194
 None
 1.12A 2bxqA-3n0gA:
2.2		 2bxqA-3n0gA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 LEU A 541
ASN A 537
ARG A 159
 None
 0.76A 2qhfA-3n0gA:
undetectable		 2qhfA-3n0gA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		5 / 11 ILE A 393
LEU A 386
ILE A 390
SER A 447
PHE A 454
 None
None
None
DST  A 601 ( 4.4A)
None
 0.97A 2w9sA-3n0gA:
undetectable		 2w9sA-3n0gA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		5 / 11 ILE A 393
LEU A 386
ILE A 390
SER A 447
PHE A 454
 None
None
None
DST  A 601 ( 4.4A)
None
 0.95A 2w9sB-3n0gA:
undetectable		 2w9sB-3n0gA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 CYH A 382
PHE A 383
PHE A 360
 None
 1.09A 3cr5X-3n0gA:
undetectable		 3cr5X-3n0gA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 PHE A 155
GLU A 168
SER A 171
ARG A 159
 None
 1.24A 3dqtA-3n0gA:
undetectable
3dqtB-3n0gA:
undetectable		 3dqtA-3n0gA:
22.14
3dqtB-3n0gA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 THR A 291
LYS A 401
GLU A 290
 None
 1.00A 3ijdB-3n0gA:
undetectable		 3ijdB-3n0gA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 8 PHE A 155
GLU A 168
SER A 171
ARG A 159
 None
 1.22A 3jx1A-3n0gA:
1.3
3jx1B-3n0gA:
undetectable		 3jx1A-3n0gA:
20.53
3jx1B-3n0gA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 SER A 171
ARG A 159
PHE A 155
GLU A 168
 None
 1.24A 3n5tA-3n0gA:
undetectable
3n5tB-3n0gA:
undetectable		 3n5tA-3n0gA:
20.70
3n5tB-3n0gA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 ASP A 209
GLU A 205
GLY A 204
 None
 0.62A 3w9tA-3n0gA:
undetectable		 3w9tA-3n0gA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 5 ASP A 209
GLU A 205
GLY A 204
GLU A 531
 None
 0.90A 3w9tC-3n0gA:
undetectable		 3w9tC-3n0gA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 6 ASP A 209
GLU A 205
GLY A 204
GLU A 531
 None
 0.90A 3w9tE-3n0gA:
undetectable		 3w9tE-3n0gA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 5 ASP A 209
GLU A 205
GLY A 204
GLU A 531
 None
 0.89A 3w9tG-3n0gA:
undetectable		 3w9tG-3n0gA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 TRP A 295
TRP A 294
THR A 291
 None
 1.45A 4bboB-3n0gA:
undetectable		 4bboB-3n0gA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 8 SER A 171
ARG A 159
ILE A 207
PHE A 155
 None
 1.23A 4cx7A-3n0gA:
undetectable
4cx7B-3n0gA:
undetectable		 4cx7A-3n0gA:
22.05
4cx7B-3n0gA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 8 SER A 171
ARG A 159
PHE A 155
GLU A 168
 None
 1.23A 4cx7A-3n0gA:
undetectable
4cx7B-3n0gA:
undetectable		 4cx7A-3n0gA:
22.05
4cx7B-3n0gA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 8 SER A 171
ARG A 159
ILE A 207
PHE A 155
 None
 1.20A 4cx7C-3n0gA:
undetectable
4cx7D-3n0gA:
undetectable		 4cx7C-3n0gA:
22.05
4cx7D-3n0gA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 PHE A 155
GLU A 168
SER A 171
ARG A 159
 None
 1.22A 4k5jA-3n0gA:
1.2
4k5jB-3n0gA:
undetectable		 4k5jA-3n0gA:
21.04
4k5jB-3n0gA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 TYR A 438
ARG A 486
SER A 506
 None
DST  A 601 (-3.1A)
None
 0.90A 4khpI-3n0gA:
undetectable
4khpJ-3n0gA:
undetectable		 4khpI-3n0gA:
14.09
4khpJ-3n0gA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 TYR A 438
ARG A 486
SER A 506
 None
DST  A 601 (-3.1A)
None
 1.05A 4lf7I-3n0gA:
undetectable
4lf7J-3n0gA:
undetectable		 4lf7I-3n0gA:
13.29
4lf7J-3n0gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		3 / 3 TYR A 438
ARG A 486
SER A 506
 None
DST  A 601 (-3.1A)
None
 1.05A 4lf8I-3n0gA:
undetectable
4lf8J-3n0gA:
undetectable		 4lf8I-3n0gA:
13.29
4lf8J-3n0gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 6 GLU A 502
ASP A 349
ASN A 489
ARG A 486
 None
MG  A 623 ( 3.2A)
DST  A 601 (-3.8A)
DST  A 601 (-3.1A)
 1.38A 4ntxA-3n0gA:
2.2
4ntxC-3n0gA:
undetectable		 4ntxA-3n0gA:
21.43
4ntxC-3n0gA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 ARG A 133
ARG A  94
ASP A 126
ILE A  97
 None
 1.17A 5a06B-3n0gA:
undetectable		 5a06B-3n0gA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		5 / 10 ASP A 345
ASP A 346
ASP A 349
ARG A 308
ASP A 490
 MG  A 623 (-3.0A)
None
MG  A 623 ( 3.2A)
DST  A 601 (-4.1A)
MG  A 622 ( 4.5A)
 1.18A 5eroC-3n0gA:
9.7		 5eroC-3n0gA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 PHE A 155
GLU A 168
SER A 171
ARG A 159
 None
 1.17A 5fj3A-3n0gA:
undetectable
5fj3B-3n0gA:
undetectable		 5fj3A-3n0gA:
21.04
5fj3B-3n0gA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 6 ILE A 347
PHE A 420
THR A 389
TRP A 294
 None
MG  A 621 ( 4.2A)
None
None
 1.40A 5g08A-3n0gA:
2.7		 5g08A-3n0gA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 5 TYR A 284
SER A 584
GLN A 248
THR A 247
 None
 1.32A 5n4iA-3n0gA:
undetectable		 5n4iA-3n0gA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		5 / 12 LEU A 200
ALA A 201
ILE A 191
ALA A 190
ALA A 152
 None
 1.12A 5n5dB-3n0gA:
undetectable		 5n5dB-3n0gA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 6 SER A 171
ARG A 159
PHE A 155
GLU A 168
 None
 1.19A 5uo8A-3n0gA:
0.0
5uo8B-3n0gA:
undetectable		 5uo8A-3n0gA:
21.35
5uo8B-3n0gA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 PHE A 155
GLU A 168
SER A 171
ARG A 159
 None
 1.17A 5vv7A-3n0gA:
1.2
5vv7B-3n0gA:
2.0		 5vv7A-3n0gA:
21.04
5vv7B-3n0gA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 PHE A 155
GLU A 168
SER A 171
ARG A 159
 None
 1.18A 5vvnA-3n0gA:
undetectable
5vvnB-3n0gA:
undetectable		 5vvnA-3n0gA:
21.04
5vvnB-3n0gA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 SER A 171
ARG A 159
PHE A 155
GLU A 168
 None
 1.18A 6av6A-3n0gA:
undetectable
6av6B-3n0gA:
0.0		 6av6A-3n0gA:
8.91
6av6B-3n0gA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 7 SER A 171
ARG A 159
PHE A 155
GLU A 168
 None
 1.15A 6av7A-3n0gA:
0.1
6av7B-3n0gA:
undetectable		 6av7A-3n0gA:
8.91
6av7B-3n0gA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		5 / 10 HIS A 237
ARG A 116
ASP A 112
GLU A 196
ARG A 156
 None
 1.47A 6b94A-3n0gA:
undetectable
6b94B-3n0gA:
undetectable		 6b94A-3n0gA:
9.20
6b94B-3n0gA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 5 LEU A 386
LEU A 450
THR A 342
ARG A 331
 None
 1.01A 6ew0F-3n0gA:
undetectable		 6ew0F-3n0gA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3n0g ISOPRENE SYNTHASE
(Populus
tremula
x
Populus
alba) 		4 / 6 LEU A 386
LEU A 450
THR A 342
ARG A 331
 None
 1.01A 6ew0G-3n0gA:
undetectable		 6ew0G-3n0gA:
9.29