SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		6 / 12 THR A 141
VAL A 143
ILE A 238
GLY A 252
ALA A 254
ILE A 217
 None
 1.42A 1bx4A-3n0rA:
undetectable		 1bx4A-3n0rA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 11 LEU A 237
LEU A 105
ALA A 250
PHE A 236
GLY A 252
 None
 1.11A 1cmaA-3n0rA:
undetectable
1cmaB-3n0rA:
undetectable		 1cmaA-3n0rA:
15.57
1cmaB-3n0rA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 ALA A  85
GLY A  28
THR A  27
ALA A  35
LEU A  79
 None
 1.18A 1jipA-3n0rA:
undetectable		 1jipA-3n0rA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 ALA A 250
PHE A 236
GLY A 252
LEU A 237
LEU A 105
 None
 1.09A 1mj2C-3n0rA:
undetectable
1mj2D-3n0rA:
undetectable		 1mj2C-3n0rA:
15.17
1mj2D-3n0rA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 10 ALA A  93
ALA A  20
ARG A  19
LEU A 105
LEU A  89
 None
 1.11A 2bxqA-3n0rA:
undetectable		 2bxqA-3n0rA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.39A 3k39A-3n0rA:
undetectable		 3k39A-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.42A 3k39B-3n0rA:
undetectable		 3k39B-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.41A 3k39E-3n0rA:
undetectable		 3k39E-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.41A 3k39F-3n0rA:
undetectable		 3k39F-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.40A 3k39G-3n0rA:
undetectable		 3k39G-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.40A 3k39H-3n0rA:
undetectable		 3k39H-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.40A 3k39M-3n0rA:
undetectable		 3k39M-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.41A 3k39N-3n0rA:
undetectable		 3k39N-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.41A 3k39O-3n0rA:
undetectable		 3k39O-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.41A 3k39P-3n0rA:
undetectable		 3k39P-3n0rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		4 / 6 ALA A 140
GLY A 187
PRO A 186
VAL A 143
 None
 0.98A 4dubA-3n0rA:
undetectable		 4dubA-3n0rA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 SER A  67
LEU A  79
ALA A  93
ASP A  24
GLY A  28
 None
 1.44A 4j7xA-3n0rA:
undetectable		 4j7xA-3n0rA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 SER A  67
LEU A  79
GLN A  98
ALA A  93
ASP A  24
 None
 1.29A 4j7xA-3n0rA:
undetectable		 4j7xA-3n0rA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		3 / 3 HIS A 165
GLY A 252
ILE A 251
 None
 0.60A 4k50A-3n0rA:
undetectable		 4k50A-3n0rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		3 / 3 HIS A 165
GLY A 252
ILE A 251
 None
 0.58A 4k50I-3n0rA:
undetectable		 4k50I-3n0rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		3 / 3 ARG A  53
HIS A  10
SER A  51
 None
 1.03A 4mjwA-3n0rA:
2.0
4mjwB-3n0rA:
1.8		 4mjwA-3n0rA:
21.20
4mjwB-3n0rA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		3 / 3 SER A  51
ARG A  53
HIS A  10
 None
 1.02A 4mjwA-3n0rA:
2.0
4mjwB-3n0rA:
1.8		 4mjwA-3n0rA:
21.20
4mjwB-3n0rA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.45A 4mwvA-3n0rA:
undetectable		 4mwvA-3n0rA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 GLU A 106
LEU A 105
ARG A  19
ARG A  16
TYR A  57
 None
 1.45A 4mx0A-3n0rA:
undetectable		 4mx0A-3n0rA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		4 / 8 ILE A 116
LEU A  39
LEU A  36
ILE A  14
 None
 0.98A 4xtaB-3n0rA:
undetectable		 4xtaB-3n0rA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		4 / 7 PHE A  60
GLY A  28
THR A  22
LEU A  89
 None
 0.94A 4zdzA-3n0rA:
undetectable		 4zdzA-3n0rA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 9 LEU A 117
LEU A 102
ALA A  62
VAL A  59
ARG A  58
 None
 1.40A 5g44A-3n0rA:
undetectable		 5g44A-3n0rA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		5 / 12 VAL A 151
PRO A 150
ALA A 153
ILE A 219
PHE A 242
 None
 1.17A 5hgcA-3n0rA:
undetectable		 5hgcA-3n0rA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3n0r RESPONSE REGULATOR
(Caulobacter
vibrioides) 		3 / 3 TYR A  17
ALA A  93
LEU A  65
 None
 0.66A 6d9kF-3n0rA:
2.3		 6d9kF-3n0rA:
19.23