SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		4 / 8 VAL A 122
TYR A 140
ASP A 128
LEU A 107
 None
 1.25A 1pk2A-3n0vA:
undetectable		 1pk2A-3n0vA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 12 PHE A 276
PHE A  66
LEU A  28
VAL A  35
VAL A  24
 None
 1.21A 1q23B-3n0vA:
undetectable		 1q23B-3n0vA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 12 PHE A 276
PHE A  66
LEU A  28
VAL A  35
VAL A  24
 None
 1.21A 1q23C-3n0vA:
undetectable		 1q23C-3n0vA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 11 PHE A 276
PHE A  66
LEU A  28
VAL A  35
VAL A  24
 None
 1.21A 1q23I-3n0vA:
undetectable		 1q23I-3n0vA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 11 PHE A 276
PHE A  66
LEU A  28
VAL A  35
VAL A  24
 None
 1.21A 1q23L-3n0vA:
undetectable		 1q23L-3n0vA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 12 VAL A  92
ILE A 170
LEU A 168
ILE A 191
ALA A 236
 None
 0.83A 2gj5A-3n0vA:
undetectable		 2gj5A-3n0vA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 12 ARG A 109
TYR A 108
ILE A  94
VAL A  92
LEU A 115
 None
 1.19A 2zzmA-3n0vA:
4.9		 2zzmA-3n0vA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		4 / 8 LEU A 168
ILE A 235
VAL A 284
GLY A 268
 None
 0.79A 4eq4B-3n0vA:
undetectable		 4eq4B-3n0vA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		4 / 6 ILE A 170
ALA A 121
VAL A 119
VAL A  96
 None
 0.89A 5eclD-3n0vA:
undetectable		 5eclD-3n0vA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		5 / 10 GLY A 268
ARG A 273
VAL A  92
PRO A  90
GLY A 116
 None
 0.98A 5vncC-3n0vA:
3.0		 5vncC-3n0vA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 3n0v FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
putida) 		4 / 6 GLN A 176
HIS A 142
ALA A 144
GLN A 153
 None
 1.23A 6f6jC-3n0vA:
undetectable
6f6jD-3n0vA:
undetectable		 6f6jC-3n0vA:
23.14
6f6jD-3n0vA:
23.14