SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		4 / 5 ASP A 126
ASP A 133
LEU A  20
LEU A 128
 None
 1.10A 1nh8A-3n0zA:
undetectable		 1nh8A-3n0zA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		4 / 6 ASN A 159
LYS A 120
GLN A  26
ILE A 123
 None
 1.07A 2jn3A-3n0zA:
2.3		 2jn3A-3n0zA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		4 / 7 ILE A  70
SER A  68
PHE A  35
PHE A   5
 3AT  A 181 ( 4.6A)
None
None
3AT  A 181 (-3.6A)
 0.93A 2q6hA-3n0zA:
undetectable		 2q6hA-3n0zA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		4 / 7 ILE A  70
SER A  68
PHE A  35
PHE A   5
 3AT  A 181 ( 4.6A)
None
None
3AT  A 181 (-3.6A)
 0.92A 2qb4A-3n0zA:
undetectable		 2qb4A-3n0zA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC608_0
(GBAA_1210 PROTEIN)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		5 / 5 GLU A  12
ARG A  63
LYS A  76
ARG A 113
GLU A 136
 MN  A 182 ( 3.4A)
3AT  A 181 (-3.0A)
3AT  A 181 (-3.4A)
3AT  A 181 (-3.1A)
MN  A 182 ( 2.1A)
 1.19A 3tj7C-3n0zA:
13.3		 3tj7C-3n0zA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		3 / 3 ASP A 126
ARG A  63
LYS A 111
 None
3AT  A 181 (-3.0A)
3AT  A 181 (-2.9A)
 1.27A 3wipG-3n0zA:
undetectable		 3wipG-3n0zA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 3n0z ADENYLATE CYCLASE 2
(Yersinia
pestis) 		3 / 3 TYR A 173
ARG A 113
LYS A 111
 3AT  A 181 (-4.0A)
3AT  A 181 (-3.1A)
3AT  A 181 (-2.9A)
 1.31A 4wq5B-3n0zA:
undetectable		 4wq5B-3n0zA:
19.35