SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 3n1b VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 54
(Mus
musculus) 		4 / 6 GLU A 856
ASP A 852
ASP A 849
LYS A 848
 None
 1.40A 3pocB-3n1bA:
undetectable		 3pocB-3n1bA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3n1b VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 54
(Mus
musculus) 		4 / 7 LEU A 959
LEU A 962
ILE A 917
MET A 865
 None
 0.82A 3u5jA-3n1bA:
undetectable		 3u5jA-3n1bA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3n1b VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 54
(Mus
musculus) 		5 / 12 ASN A 955
ILE A 901
ASN A 918
LEU A 959
SER A 858
 None
 1.30A 4pooA-3n1bA:
2.1		 4pooA-3n1bA:
21.00