SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 3n1g BROTHER OF CDO
(Homo
sapiens) 		3 / 3 ARG C 753
TYR C 763
LYS C 789
 None
 1.07A 1uujB-3n1gC:
undetectable		 1uujB-3n1gC:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 3n1g BROTHER OF CDO
(Homo
sapiens) 		4 / 8 ARG C 711
THR C 743
GLY C 796
ILE C 745
 None
 0.96A 2f9wA-3n1gC:
undetectable
2f9wB-3n1gC:
undetectable		 2f9wA-3n1gC:
15.47
2f9wB-3n1gC:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 3n1g BROTHER OF CDO
(Homo
sapiens) 		3 / 3 ARG C 812
GLN C 781
PRO C 782
 None
 0.83A 2qhfA-3n1gC:
undetectable		 2qhfA-3n1gC:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3n1g BROTHER OF CDO
(Homo
sapiens) 		4 / 8 GLY C 796
THR C 743
ASN C 794
ARG C 711
 None
 1.07A 4m5mA-3n1gC:
undetectable		 4m5mA-3n1gC:
20.36